Kathryn Baldyga BA, Ike Iloputaife BS, George Taffet MD, Nicole LaGanke BSc, Brad Manor PhD, Lewis A. Lipsitz MD, Courtney L. Millar PhD
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引用次数: 0
摘要
背景:招募老年人参与临床试验尤其具有挑战性。我们的目的是确定有针对性的网络广告是否是一种有效的招募策略:我们比较了三项有代表性的涉及老年人的临床试验中传统方法和有针对性的网络方法的招募率。所有研究最初都采用了传统的招募方法,但在经历了缓慢的招募率之后,主要转向了有针对性的网络广告:结果:我们发现,与传统方法相比,网络广告的受众更多。与传统方法相比,基于网络的方法在表达兴趣、完成电话和面对面筛选、资格审查和注册方面的比率也至少是传统方法的两倍。此外,电话筛查后被排除在外的人员比例并没有因每项研究中使用了有针对性的网络广告(STAMINA:51%;Berry and Steps:62%;ISTIM:20%)还是传统方法(STAMINA:48%;Berry and Steps:69%;ISTIM:23%)而有所不同。与传统方法相比,使用网络广告招募到的人往往更年轻,但在种族分布和教育程度方面相似:与传统招募方法相比,有针对性的网络广告在招募老年人参与临床试验方面可能更有效,但还需要进一步评估研究设计的兼容性、潜在的人群偏差以及成本效益。
Comparison of targeted web-based advertising versus traditional methods for recruiting older adults into clinical trials
Background
Recruiting older adults into clinical trials can be particularly challenging. Our objective was to determine if targeted web-based advertising is an effective recruitment strategy.
Methods
We compared the recruitment rates of traditional and targeted web-based methods for three representative clinical trials involving older adults. All studies utilized traditional recruitment methods initially, but shifted toward primarily targeted web-based advertising after experiencing slow recruitment rates.
Results
We found that web-based advertising reached more individuals compared to traditional methods. Compared to traditional methods, web-based methods also had at least twice the rate of expressed interest, completion of telephone and in-person screening, eligibility, and enrollment. Additionally, the proportion of individuals excluded after the telephone screening did not differ according to whether targeted web-based advertising (STAMINA: 51%; Berries and Steps: 62%; ISTIM: 20%) or traditional methods (STAMINA: 48%; Berries and Steps: 69%; ISTIM: 23%) were used within each study. Those recruited using web-based advertisements tended to be younger compared to traditional methods, but were similar in racial distribution and education.
Conclusion
Targeted web-based advertisements may be more effective in recruiting older adults for clinical trials at a faster rate than traditional recruitment methods, but need further evaluation of compatible study designs, potential population bias, and cost-effectiveness.
期刊介绍:
Journal of the American Geriatrics Society (JAGS) is the go-to journal for clinical aging research. We provide a diverse, interprofessional community of healthcare professionals with the latest insights on geriatrics education, clinical practice, and public policy—all supporting the high-quality, person-centered care essential to our well-being as we age. Since the publication of our first edition in 1953, JAGS has remained one of the oldest and most impactful journals dedicated exclusively to gerontology and geriatrics.