Shujie Lin , Xiang Yu , Ziliang Zhang , Yahan Zhang , Junyi Chen , Chunju Li , Qingbin Meng
{"title":"巨型大环通过宿主--客体复合物克服光辉菊酯的后处理光毒性","authors":"Shujie Lin , Xiang Yu , Ziliang Zhang , Yahan Zhang , Junyi Chen , Chunju Li , Qingbin Meng","doi":"10.1039/d4cc04777j","DOIUrl":null,"url":null,"abstract":"<div><div>Here we reported a supramolecular sequestration strategy to overcome the post-treatment phototoxicity of photofrin <em>via</em> direct host–guest complexation. Efficient recognition potency of a giant pentaphen[3]arene derivative could favor suppressing sunlight-induced skin damage through weakening the ability of complexed photofrin to generate singlet oxygen.</div></div>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"60 93","pages":"Pages 13686-13689"},"PeriodicalIF":4.3000,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A giant macrocycle overcomes the post-treatment phototoxicity of photofrin through host–guest complexation†\",\"authors\":\"Shujie Lin , Xiang Yu , Ziliang Zhang , Yahan Zhang , Junyi Chen , Chunju Li , Qingbin Meng\",\"doi\":\"10.1039/d4cc04777j\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Here we reported a supramolecular sequestration strategy to overcome the post-treatment phototoxicity of photofrin <em>via</em> direct host–guest complexation. Efficient recognition potency of a giant pentaphen[3]arene derivative could favor suppressing sunlight-induced skin damage through weakening the ability of complexed photofrin to generate singlet oxygen.</div></div>\",\"PeriodicalId\":67,\"journal\":{\"name\":\"Chemical Communications\",\"volume\":\"60 93\",\"pages\":\"Pages 13686-13689\"},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2024-10-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical Communications\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S1359734524022717\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/10/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1359734524022717","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/25 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
A giant macrocycle overcomes the post-treatment phototoxicity of photofrin through host–guest complexation†
Here we reported a supramolecular sequestration strategy to overcome the post-treatment phototoxicity of photofrin via direct host–guest complexation. Efficient recognition potency of a giant pentaphen[3]arene derivative could favor suppressing sunlight-induced skin damage through weakening the ability of complexed photofrin to generate singlet oxygen.
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