{"title":"药物再利用的可解释基础模型","authors":"Alaa Bessadok, Francesca Grisoni","doi":"10.1038/s41591-024-03333-8","DOIUrl":null,"url":null,"abstract":"A foundation model leverages large-scale medical knowledge to repurpose drugs for diseases that currently lack approved treatments, and provides explanations to support clinicians’ decisions.","PeriodicalId":58,"journal":{"name":"The Journal of Physical Chemistry ","volume":"35 1","pages":""},"PeriodicalIF":2.7810,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An explainable foundation model for drug repurposing\",\"authors\":\"Alaa Bessadok, Francesca Grisoni\",\"doi\":\"10.1038/s41591-024-03333-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A foundation model leverages large-scale medical knowledge to repurpose drugs for diseases that currently lack approved treatments, and provides explanations to support clinicians’ decisions.\",\"PeriodicalId\":58,\"journal\":{\"name\":\"The Journal of Physical Chemistry \",\"volume\":\"35 1\",\"pages\":\"\"},\"PeriodicalIF\":2.7810,\"publicationDate\":\"2024-10-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Physical Chemistry \",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41591-024-03333-8\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Physical Chemistry ","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41591-024-03333-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
An explainable foundation model for drug repurposing
A foundation model leverages large-scale medical knowledge to repurpose drugs for diseases that currently lack approved treatments, and provides explanations to support clinicians’ decisions.
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