挪威为期两年的坚定社区治疗的临床结果和结果预测因素:一项探索性前瞻性事后研究。

IF 3.4 2区 医学 Q2 PSYCHIATRY BMC Psychiatry Pub Date : 2024-10-24 DOI:10.1186/s12888-024-06181-5
Torleif Ruud, Maria Lie Selle, Hanne K Clausen, Kristin S Heiervang, Sigrun Odden, Hanne Kilen Stuen, Anne Landheim
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引用次数: 0

摘要

背景:在许多高收入国家,自主社区治疗(ACT)小组已成为为严重精神病患者提供心理健康服务的一部分。一些国家对ACT的治疗效果进行了研究,挪威也需要了解ACT团队的治疗效果。我们的目的是研究ACT的临床疗效、疗效与患者和治疗特点的关系,以及不同ACT团队的疗效是否存在差异:我们的探索性、前瞻性、事前-事后多中心研究涉及142名患者,他们在挪威城乡地区成立的首批12个ACT团队中接受了为期两年的ACT治疗。没有对照组。主要结果是临床医生评定的精神症状变化。次要结果是临床医生评定的功能和参与度的变化,以及与接受 ACT 治疗前两年相比社区居住权的变化。我们使用 "支持性社区治疗测量工具"(Tool for Measurement of Assertive Community Treatment)对 ACT 模式的忠实性进行了测量。我们采用线性混合效应模型来分析结果及其与患者特征和治疗的关系:两年后,精神症状明显减轻,但影响程度较小。阴性症状、焦虑和抑郁、躁动和躁狂均有明显减轻,而阳性症状则无明显变化。功能、参与度和社区保有权均有明显提高,但影响程度较小。年龄、参与困难、酗酒问题、以前经常使用住院服务、治疗总次数以及团队对 ACT 模式的忠诚度与不同症状组相关。功能改善程度较低与治疗小组的忠诚度和治疗次数有关。参与度的变化与任何预测因素都无关。较年轻的患者和在治疗开始时接受社区治疗的患者的社区居住时间增加较多:结论:为期两年的 ACT 治疗在精神症状、功能、参与度和社区居住方面取得了显著的积极成果,但影响程度较小。这些结果与一些潜在的预测因素有关,并且出现了一些团队层面的差异。两年后的积极显著结果表明,ACT 团队的长期治疗可能会取得更大的改善。
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Clinical outcomes and outcome predictors of two-year assertive community treatment in Norway: an explorative prospective pre-post study.

Background: Assertive Community Treatment (ACT) teams have become a part of mental health services for people with severe mental illness in many high-income countries. Studies in several countries have investigated the outcomes of ACT, and knowledge is also needed about outcomes of ACT teams in Norway. Our aims were to study clinical outcomes of ACT, how the outcomes were associated with characteristics of patients and treatment, and whether they differed across ACT teams.

Methods: Our explorative, prospective, pre-post multicenter study involved 142 patients who received ACT for two years from the first 12 ACT teams established in urban and rural areas of Norway. There was no control group. The primary outcome was change in clinician-rated psychiatric symptoms. Secondary outcomes were clinician-rated change in functioning and engagement and change in community tenure compared with 2 years prior to ACT. We measured fidelity to the ACT model using the Tool for Measurement of Assertive Community Treatment. We performed linear mixed-effects modeling to analyze outcomes and their associations with characteristics of patients and treatment.

Results: After two years, psychiatric symptoms were significantly reduced with a small effect size. Negative symptoms, anxiety and depression, and agitation and mania had significant reductions, while positive symptoms had nonsignificant changes. Functioning, engagement, and community tenure all significantly increased with small effect sizes. Age, difficulty to engage, problematic use of alcohol, frequent previous use of inpatient services, total number of sessions, and team's fidelity to the ACT model were associated with different groups of symptoms. Less improvement in functioning was associated with team fidelity and number of sessions. Change in engagement was not associated with any predictors. Increased community tenure was greater for younger patients and patients who were on community treatment orders at treatment start.

Conclusions: ACT for two years led to significant positive outcomes with small effect sizes for psychiatric symptoms, functioning, engagement, and community tenure. The outcomes were associated with some potential predictors, and some team-level variance emerged. Positive significant outcomes after two years indicate that larger improvements may be achieved from longer-term treatments by ACT teams.

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来源期刊
BMC Psychiatry
BMC Psychiatry 医学-精神病学
CiteScore
5.90
自引率
4.50%
发文量
716
审稿时长
3-6 weeks
期刊介绍: BMC Psychiatry is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of psychiatric disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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