首次输血年龄对极低和极低出生体重儿脑室内出血的影响。

IF 2.3 4区 医学 Q2 HEMATOLOGY Expert Review of Hematology Pub Date : 2024-11-01 Epub Date: 2024-11-12 DOI:10.1080/17474086.2024.2422017
Yuping Qian, Jingwei Huang, Huanhuan Cheng, Juan Wang
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引用次数: 0

摘要

背景:早产儿血容量低,造血系统发育不完善,因此是输血对象的一个群体。本研究的目的是探究首次输血年龄天数对极低和极低出生体重 VLBW 婴儿和 ELBW 婴儿脑室内出血(IVH)的影响:对 150 名接受过输血的 VLBW 和 ELBW 婴儿的数据进行回顾。分为 IVH 组和非 IVH 组。对婴儿及其母亲的一般数据、输血相关数据、IVH 危险因素以及相关因素对 IVH 的预测价值进行了分析:结果:IVH组婴儿的出生体重、入院时血红蛋白水平和首次输血天数较低,5分钟Apgar评分≤7分和早期输血率较高。自然分娩和 5 分钟 Apgar 评分≤7 分是 IVH 的风险因素。出生体重和首次输血年龄天数对VLBW和ELBW婴儿的IVH有预测价值:结论:首次输血年龄越小,IVH 风险越高。结论:首次输血年龄越小,IVH 风险越高,因此有必要推迟首次输血年龄,减少早期输血。
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Effect of days of age at first blood transfusion on intraventricular hemorrhage in very low and extremely low birth weight infants.

Background: Preterm infants are a group cohort of transfusion recipients due to their low blood volume and underdeveloped hematopoietic system. The objective of this study was to probe the effect of days of age at first blood transfusion on intraventricular hemorrhage (IVH) in very low and extremely low birth weight VLBW and ELBW infants.

Research design and methods: Data of 150 VLBW and ELBW infants receiving blood transfusions were reviewed. IVH and non-IVH groups were established. General data on infants and their mothers and data related to blood transfusion, IVH risk factors, and the predictive value of the relevant factors for IVH were analyzed.

Results: The IVH group had lower birth weight, hemoglobin levels on admission, and days of age at first blood transfusion and higher 5-min Apgar score ≤7 points and early transfusion rate. Spontaneous delivery and 5-min Apgar score ≤7 points were risk factors for IVH. Birth weight and days of age at first blood transfusion had predictive value for IVH in VLBW and ELBW infants.

Conclusions: The younger the days of age at first blood transfusion, the higher the IVH risk. It is necessary to delay the days of age at first blood transfusion and reduce early blood transfusion.

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来源期刊
CiteScore
4.70
自引率
3.60%
发文量
98
审稿时长
6-12 weeks
期刊介绍: Advanced molecular research techniques have transformed hematology in recent years. With improved understanding of hematologic diseases, we now have the opportunity to research and evaluate new biological therapies, new drugs and drug combinations, new treatment schedules and novel approaches including stem cell transplantation. We can also expect proteomics, molecular genetics and biomarker research to facilitate new diagnostic approaches and the identification of appropriate therapies. Further advances in our knowledge regarding the formation and function of blood cells and blood-forming tissues should ensue, and it will be a major challenge for hematologists to adopt these new paradigms and develop integrated strategies to define the best possible patient care. Expert Review of Hematology (1747-4086) puts these advances in context and explores how they will translate directly into clinical practice.
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