埃塞俄比亚东部新生儿重症监护室新生儿早期死亡的流行病学:来自 Hiwot Fana 大学专科医院的启示。

IF 1.4 Q3 PEDIATRICS Global Pediatric Health Pub Date : 2024-10-17 eCollection Date: 2024-01-01 DOI:10.1177/2333794X241273134
AbdulmalikAbdela Bushra, NegaAssefa Kassa, Desalegn Admassu Ayana, Adisu Birhanu Weldesenbet, Mohammedin KebirHussen KebirMuhammad, Biniam Petros Chunkele, Ibsa Abdusemed Ahmed, Alo Edin Huka
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引用次数: 0

摘要

背景。在埃塞俄比亚,新生儿早期死亡仍是一项重大的公共卫生挑战。因此,本研究旨在调查埃塞俄比亚东部 Hiwot Fana 大学专科医院新生儿重症监护室收治的婴儿中新生儿早期死亡的程度和相关因素。方法:2018 年 9 月 11 日至 2021 年 9 月 10 日期间收治的 432 名新生儿的病历,于 11 月 20 日至 12 月 20 日进行了一项基于机构的横断面研究。数据经清理后输入 Epi Data 3.1,并使用 Stata 15 进行分析。采用二变量和多变量逻辑回归分析,统计显著性设定为 P 值 结果。研究发现,新生儿早期死亡率为 10.6%(95% CI:8.06, 13.94)。导致早期新生儿死亡的主要因素是早发新生儿败血症(56%)、早产(52.2%)和围产期窒息(32.6%)。值得注意的是,早发新生儿败血症(调整比值比 [AOR] = 2.31,95% 置信区间 [CI]:1.06, 5.05)、呼吸窘迫综合征(AOR = 3.98,95% CI:1.97, 8.05)和低出生体重(AOR = 3.70,95% CI:1.67, 8.18)与新生儿早期死亡独立相关。结论该研究重点探讨了埃塞俄比亚新生儿早期死亡的重要意义,而新生儿早期败血症、呼吸窘迫综合征和低出生体重等关键因素是造成这一问题的原因。预防性干预措施和高危新生儿早期管理方面的进步为减少新生儿早期死亡带来了希望。
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Epidemiology of Early Neonatal Mortality in an Eastern Ethiopian NICU: Insights From Hiwot Fana Specialized University Hospital.

Background. Early neonatal mortality remains a significant public health challenge in Ethiopia. Therefore, this study is designed to investigate the magnitude and underlying factors associated with early neonatal mortality among infants admitted to the Neonatal Intensive Care Unit at Hiwot Fana Specialized University Hospital in Eastern Ethiopia. Methods. an institutional-based cross-sectional study was conducted from November 20 to December 20, 2021, by reviewing the medical records of 432 neonates admitted from September 11, 2018, to September 10, 2021. Data were cleaned, entered into Epi Data 3.1, and analyzed using Stata 15. Bivariable and multivariable logistic regression analyses were employed with statistical significance set at a P-value <.05. Results. The study found that the magnitude of early neonatal mortality was 10.6% (95% CI: 8.06, 13.94). The primary contributors to early neonatal mortality was early onset neonatal sepsis (56%), preterm birth (52.2%), and perinatal asphyxia (32.6%). Notably, early onset neonatal sepsis (Adjusted Odds Ratio [AOR] = 2.31, 95% confidence interval [CI]: 1.06, 5.05), respiratory distress syndrome (AOR = 3.98, 95% CI: 1.97, 8.05), and low birth weight (AOR = 3.70, 95% CI: 1.67, 8.18) were independently associated with early neonatal mortality. Conclusion. The study focuses on the significance of early neonatal mortality in Ethiopia, with key factors such as early onset neonatal sepsis, respiratory distress syndrome, and low birth weight contributing to this issue. The advancements in preventive interventions and early management of high-risk neonates offer promise in reducing early neonatal deaths.

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来源期刊
Global Pediatric Health
Global Pediatric Health Nursing-Pediatrics
CiteScore
2.20
自引率
0.00%
发文量
105
审稿时长
12 weeks
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