在非亲缘造血细胞供体和受体中发现八个新的 HLA I 类等位基因

IF 5.9 4区医学 Q2 CELL BIOLOGY HLA Pub Date : 2024-10-28 DOI:10.1111/tan.15734

Elizabeth J. Minshall, Charlotte A. Cambridge, Sebastian J. F. Hopper, Steven G. E. Marsh, Neema P. Mayor

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摘要

通过全基因测序，确定了 8 个新型 HLA I 类等位基因。

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Eight Novel HLA Class I Alleles Identified in Unrelated Haematopoietic Cell Donors and Recipients

Eight novel HLA class I alleles have been identified using full gene sequencing.

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来源期刊

HLA Immunology and Microbiology-Immunology

CiteScore

3.00

自引率

28.80%

发文量

368

期刊介绍： HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.