使用肉毒杆菌毒素或/和热成型咬合夹板治疗中度睡眠呼吸暂停和夜间磨牙症后患者的满意度:试点研究。

IF 3 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Journal of Personalized Medicine Pub Date : 2024-09-26 DOI:10.3390/jpm14101029
Taalat Gabriel Rezk Gavrilă, Anamaria Bechir, Andrada Camelia Nicolau, Edwin Sever Bechir
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引用次数: 0

摘要

背景:睡眠呼吸暂停和夜间磨牙症属于睡眠障碍,会影响生活质量。本研究旨在探讨肉毒杆菌毒素注射作为单一疗法或与佩戴热成型咬合夹板相结合对中度睡眠呼吸暂停和夜间磨牙症患者的影响,并确定患者在应用治疗后的满意度。研究方法选取的研究对象分为两组:第一组患者(18 人)的治疗包括在咀嚼肌注射肉毒杆菌毒素(Allergan)作为单一疗法;第二组患者(18 人)的治疗包括在咀嚼肌注射肉毒杆菌毒素和佩戴热成型咬合夹板。分别在基线、三周、三个月和六个月后对治疗效果进行监测。结果显示与单一疗法相比,联合疗法在减轻所研究的症状方面效果更好。两种疗法都提高了患者的满意度。结论用于治疗中度睡眠呼吸暂停和睡眠磨牙症特定症状的疗法是有效的。两组患者在接受治疗后的满意度都很高,但联合疗法的效果优于单一疗法。
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Patients' Satisfaction after the Treatment of Moderate Sleep Apnea and Nocturnal Bruxism with Botox or/and Thermoformed Occlusal Splints: A Pilot Study.

Background: Sleep apnea and nocturnal bruxism belong to sleep disorders that can affect the quality of life. The aim of this study was to investigate the effects on patients with moderate sleep apnea and nocturnal bruxism of Botox injection as monotherapy or associated with wearing thermoformed occlusal splints and to determine the patients' satisfaction degree after the applied treatments. Methods: The selected patients for study were divided into two groups: in the first group, the patients (n = 18) treatment consisted of injecting Botox (Allergan) into the masseter muscle as monotherapy; in the second group, the patients (n = 18) benefited from associated therapy, Botox injections in masseter muscle, and the wear of thermoformed occlusal splints. At baseline, at three weeks, at three months, and six months after the effectuation of therapies, the monitoring sessions were realized. Results: The associated therapy presented better results in decreasing the studied symptoms than the monotherapy. Both therapies improved patient satisfaction. Conclusions: The applied therapies for treating the specific symptomatology in moderate sleep apnea and sleep bruxism were efficacious. Patient satisfaction was very good in both groups after the applied treatments, but the associated therapy presented better results than monotherapy.

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来源期刊
Journal of Personalized Medicine
Journal of Personalized Medicine Medicine-Medicine (miscellaneous)
CiteScore
4.10
自引率
0.00%
发文量
1878
审稿时长
11 weeks
期刊介绍: Journal of Personalized Medicine (JPM; ISSN 2075-4426) is an international, open access journal aimed at bringing all aspects of personalized medicine to one platform. JPM publishes cutting edge, innovative preclinical and translational scientific research and technologies related to personalized medicine (e.g., pharmacogenomics/proteomics, systems biology). JPM recognizes that personalized medicine—the assessment of genetic, environmental and host factors that cause variability of individuals—is a challenging, transdisciplinary topic that requires discussions from a range of experts. For a comprehensive perspective of personalized medicine, JPM aims to integrate expertise from the molecular and translational sciences, therapeutics and diagnostics, as well as discussions of regulatory, social, ethical and policy aspects. We provide a forum to bring together academic and clinical researchers, biotechnology, diagnostic and pharmaceutical companies, health professionals, regulatory and ethical experts, and government and regulatory authorities.
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