Mumtahin-ul Kousar , Mifftha Yaseen , Monisa Yousouf , Mudasir Ahmad Malik , Aarizoo Mushtaq , Taha Mukhtar , Rifat Javaid , Anam Aijaz , Abida Jabeen , Tawheed Amin
{"title":"谷物产品中的黄曲霉毒素--发生、检测和健康影响概述。","authors":"Mumtahin-ul Kousar , Mifftha Yaseen , Monisa Yousouf , Mudasir Ahmad Malik , Aarizoo Mushtaq , Taha Mukhtar , Rifat Javaid , Anam Aijaz , Abida Jabeen , Tawheed Amin","doi":"10.1016/j.toxicon.2024.108148","DOIUrl":null,"url":null,"abstract":"<div><div>Aflatoxins are naturally produced toxins by specific molds, namely <em>Aspergillus flavus</em> and <em>Aspergillus parasiticus</em>. These toxins can be found in various agricultural products, including crops like maize, peanuts, cottonseed, and tree nuts. They have the potential to contaminate the food supply during different stages of production, processing, and storage. Aflatoxin is a very poisonous substance that has been linked to adverse health effects in both humans and animals. It is essential to detect and monitor aflatoxins to ensure the safety of food. Efficient and precise analytical techniques, such as chromatography and immunoassays, have been used to accurately measure the levels of aflatoxins in different substances. Regulatory bodies and worldwide associations have determined maximum permissible limits for aflatoxins in food and nourishment products to protect the well-being of the general public. Effectively addressing aflatoxin contamination necessitates a comprehensive approach that encompasses various strategies in agriculture, post-harvest practices, and regulatory measures. Continuous research and collaborative endeavors are crucial in order to minimize aflatoxin exposure and mitigate the associated risks. This review offers a comprehensive examination of the presence, health consequences, and elimination techniques associated with aflatoxins.</div></div>","PeriodicalId":23289,"journal":{"name":"Toxicon","volume":"251 ","pages":"Article 108148"},"PeriodicalIF":2.6000,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Aflatoxins in cereal based products-an overview of occurrence, detection and health implication\",\"authors\":\"Mumtahin-ul Kousar , Mifftha Yaseen , Monisa Yousouf , Mudasir Ahmad Malik , Aarizoo Mushtaq , Taha Mukhtar , Rifat Javaid , Anam Aijaz , Abida Jabeen , Tawheed Amin\",\"doi\":\"10.1016/j.toxicon.2024.108148\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Aflatoxins are naturally produced toxins by specific molds, namely <em>Aspergillus flavus</em> and <em>Aspergillus parasiticus</em>. These toxins can be found in various agricultural products, including crops like maize, peanuts, cottonseed, and tree nuts. They have the potential to contaminate the food supply during different stages of production, processing, and storage. Aflatoxin is a very poisonous substance that has been linked to adverse health effects in both humans and animals. It is essential to detect and monitor aflatoxins to ensure the safety of food. Efficient and precise analytical techniques, such as chromatography and immunoassays, have been used to accurately measure the levels of aflatoxins in different substances. Regulatory bodies and worldwide associations have determined maximum permissible limits for aflatoxins in food and nourishment products to protect the well-being of the general public. Effectively addressing aflatoxin contamination necessitates a comprehensive approach that encompasses various strategies in agriculture, post-harvest practices, and regulatory measures. Continuous research and collaborative endeavors are crucial in order to minimize aflatoxin exposure and mitigate the associated risks. This review offers a comprehensive examination of the presence, health consequences, and elimination techniques associated with aflatoxins.</div></div>\",\"PeriodicalId\":23289,\"journal\":{\"name\":\"Toxicon\",\"volume\":\"251 \",\"pages\":\"Article 108148\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-10-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Toxicon\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0041010124007207\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicon","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0041010124007207","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Aflatoxins in cereal based products-an overview of occurrence, detection and health implication
Aflatoxins are naturally produced toxins by specific molds, namely Aspergillus flavus and Aspergillus parasiticus. These toxins can be found in various agricultural products, including crops like maize, peanuts, cottonseed, and tree nuts. They have the potential to contaminate the food supply during different stages of production, processing, and storage. Aflatoxin is a very poisonous substance that has been linked to adverse health effects in both humans and animals. It is essential to detect and monitor aflatoxins to ensure the safety of food. Efficient and precise analytical techniques, such as chromatography and immunoassays, have been used to accurately measure the levels of aflatoxins in different substances. Regulatory bodies and worldwide associations have determined maximum permissible limits for aflatoxins in food and nourishment products to protect the well-being of the general public. Effectively addressing aflatoxin contamination necessitates a comprehensive approach that encompasses various strategies in agriculture, post-harvest practices, and regulatory measures. Continuous research and collaborative endeavors are crucial in order to minimize aflatoxin exposure and mitigate the associated risks. This review offers a comprehensive examination of the presence, health consequences, and elimination techniques associated with aflatoxins.
期刊介绍:
Toxicon has an open access mirror Toxicon: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. An introductory offer Toxicon: X - full waiver of the Open Access fee.
Toxicon''s "aims and scope" are to publish:
-articles containing the results of original research on problems related to toxins derived from animals, plants and microorganisms
-papers on novel findings related to the chemical, pharmacological, toxicological, and immunological properties of natural toxins
-molecular biological studies of toxins and other genes from poisonous and venomous organisms that advance understanding of the role or function of toxins
-clinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtained.
-material on the use of toxins as tools in studying biological processes and material on subjects related to venom and antivenom problems.
-articles on the translational application of toxins, for example as drugs and insecticides
-epidemiological studies on envenoming or poisoning, so long as they highlight a previously unrecognised medical problem or provide insight into the prevention or medical treatment of envenoming or poisoning. Retrospective surveys of hospital records, especially those lacking species identification, will not be considered for publication. Properly designed prospective community-based surveys are strongly encouraged.
-articles describing well-known activities of venoms, such as antibacterial, anticancer, and analgesic activities of arachnid venoms, without any attempt to define the mechanism of action or purify the active component, will not be considered for publication in Toxicon.
-review articles on problems related to toxinology.
To encourage the exchange of ideas, sections of the journal may be devoted to Short Communications, Letters to the Editor and activities of the affiliated societies.