大麻合法化带来的临床和公共安全风险以及法医精神病患者使用大麻的频率。

IF 4.4 2区 医学 Q1 SUBSTANCE ABUSE International Journal of Drug Policy Pub Date : 2024-10-21 DOI:10.1016/j.drugpo.2024.104622
Stephanie R. Penney , Roland M. Jones , Treena Wilkie , Cory Gerritsen , Sumeeta Chatterjee , Gary A. Chaimowitz , Alexander I.F. Simpson
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引用次数: 0

摘要

背景:人们一直在关注加拿大大麻合法化和商业化对弱势群体的影响,例如对严重精神疾病患者(包括精神分裂症谱系障碍患者和法医精神健康服务使用者)的影响。本研究的主要目的是调查大麻合法化对安大略省法医病人样本(N = 187)的潜在危害和精神健康相关影响:我们采用伪前瞻性设计,调查了在立法改革前两年和立法改革后两年的四年时间内使用大麻的频率。我们还记录了同期的临床和公共安全结果(即精神健康恶化、在法医系统的住院时间、再次入院率、受害和暴力事件),以检验这些变量与大麻使用率之间的关系:我们发现,在研究期间,有三分之一的患者自述或通过尿检发现曾吸食大麻。在大麻合法化前,使用频率较低,合法化后则逐渐显著增加。与未吸食大麻的患者相比,吸食过一次或多次大麻的患者更有可能再次入院,其暴力行为的静态风险因素也更高。不过,没有观察到使用和不使用大麻的病人之间在实际暴力发生率上存在差异,也没有观察到随着时间推移暴力发生率上的差异。使用大麻的患者中有一半以上在使用大麻后一周内精神健康状况恶化:结论:SMI 患者吸食大麻与不良临床结果有关。这项研究的结果表明,自大麻合法化以来,与吸食大麻相关的心理健康负担在临床康复延迟和法医系统的进展方面都有所上升。
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Clinical and public safety risks associated with cannabis legalization and frequency of cannabis use among forensic mental health patients

Background

There are ongoing concerns regarding the impact of Canada's cannabis legalization and commercialization on vulnerable persons such as those with serious forms of mental illness, including persons with schizophrenia-spectrum disorders and users of forensic mental health services. The primary objective of this study was to investigate the potential harms and mental health-related impacts associated with cannabis legalization on a sample of forensic patients in Ontario (N = 187).

Methods

Using a pseudo-prospective design, we investigated the frequency of cannabis use over a four-year period encompassing two years preceding and two years following the legislative change. We recorded clinical and public safety outcomes (i.e., mental health deterioration, length of stay in the forensic system, rates of hospital readmission, victimization and violence) over the same period to test relationships between these variables and rates of cannabis use.

Results

We found that one-third of patients either self-reported or were discovered, via urine testing, to have used cannabis over the study period. Frequency of use was lower in the pre-legalization period, and then gradually and significantly increased after legalization. Compared to patients with no cannabis use, those with one or more instances of use were more likely to be readmitted to hospital and had higher rated static risk factors for violence. However, there were no observed differences in the actual rate of violence between patients using and not using cannabis, nor differences in the rate of violence over time. Over half of the patients who used cannabis experienced a worsening of their mental health status in the week following use.

Conclusions

Cannabis use among those with SMI is associated with adverse clinical outcomes. Results from this study suggest that the mental health burdens associated with cannabis use have risen in terms of delayed clinical recovery and progress through the forensic system since legalization.
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来源期刊
CiteScore
7.80
自引率
11.40%
发文量
307
审稿时长
62 days
期刊介绍: The International Journal of Drug Policy provides a forum for the dissemination of current research, reviews, debate, and critical analysis on drug use and drug policy in a global context. It seeks to publish material on the social, political, legal, and health contexts of psychoactive substance use, both licit and illicit. The journal is particularly concerned to explore the effects of drug policy and practice on drug-using behaviour and its health and social consequences. It is the policy of the journal to represent a wide range of material on drug-related matters from around the world.
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