晚期诺伍德手术后的院内和阶段间死亡率:在时间紧迫的情况下认识风险。

IF 2 4区 医学 Q2 PEDIATRICS Children-Basel Pub Date : 2024-10-18 DOI:10.3390/children11101262
Andreea Alina Andronache, Roberta Di Cosola, Martina Evangelista, Sara Boveri, Laura Schianchi, Alessandro Giamberti, Massimo Chessa
{"title":"晚期诺伍德手术后的院内和阶段间死亡率:在时间紧迫的情况下认识风险。","authors":"Andreea Alina Andronache, Roberta Di Cosola, Martina Evangelista, Sara Boveri, Laura Schianchi, Alessandro Giamberti, Massimo Chessa","doi":"10.3390/children11101262","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>A Norwood procedure performed after 14 days of life is notably burdened by a high mortality. We analysed the real risk and which other factors influence the mortality in late Norwood procedures.</p><p><strong>Methods: </strong>A single-centre, retrospective review of a series of consecutive patients who underwent a surgical Norwood procedure from January 2019 until December 2023. The patients' characteristics were considered to identify the factors associated with in-hospital and interstage mortality.</p><p><strong>Results: </strong>35 patients were included and 71% (25) of the patients underwent the Norwood procedure after 14 days of life. The median age was 27 days (6-259 days). The in-hospital mortality was 26% (9/35) with 89% (8) of the deceased being older than 15 days at the time of the surgery. Other factors that negatively affected the outcome were a restrictive interatrial septum defect (ASD) in 66% of all patients (23), the need for mechanical ventilation in 46% (16) and systemic infection prior to surgery in 43% (15).</p><p><strong>Conclusions: </strong>Age at the time of Norwood was not associated with a higher risk of mortality, but other factors such as restrictive ASD, preoperative infection and the need for mechanical ventilation prior to surgery are even more important in predicting the short-term outcome.</p>","PeriodicalId":48588,"journal":{"name":"Children-Basel","volume":"11 10","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11506364/pdf/","citationCount":"0","resultStr":"{\"title\":\"In-Hospital and Interstage Mortality After Late Norwood Procedure: Acknowledging the Risks When We Are Running Out of Time.\",\"authors\":\"Andreea Alina Andronache, Roberta Di Cosola, Martina Evangelista, Sara Boveri, Laura Schianchi, Alessandro Giamberti, Massimo Chessa\",\"doi\":\"10.3390/children11101262\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>A Norwood procedure performed after 14 days of life is notably burdened by a high mortality. We analysed the real risk and which other factors influence the mortality in late Norwood procedures.</p><p><strong>Methods: </strong>A single-centre, retrospective review of a series of consecutive patients who underwent a surgical Norwood procedure from January 2019 until December 2023. The patients' characteristics were considered to identify the factors associated with in-hospital and interstage mortality.</p><p><strong>Results: </strong>35 patients were included and 71% (25) of the patients underwent the Norwood procedure after 14 days of life. The median age was 27 days (6-259 days). The in-hospital mortality was 26% (9/35) with 89% (8) of the deceased being older than 15 days at the time of the surgery. Other factors that negatively affected the outcome were a restrictive interatrial septum defect (ASD) in 66% of all patients (23), the need for mechanical ventilation in 46% (16) and systemic infection prior to surgery in 43% (15).</p><p><strong>Conclusions: </strong>Age at the time of Norwood was not associated with a higher risk of mortality, but other factors such as restrictive ASD, preoperative infection and the need for mechanical ventilation prior to surgery are even more important in predicting the short-term outcome.</p>\",\"PeriodicalId\":48588,\"journal\":{\"name\":\"Children-Basel\",\"volume\":\"11 10\",\"pages\":\"\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2024-10-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11506364/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Children-Basel\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3390/children11101262\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Children-Basel","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/children11101262","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0

摘要

背景:出生 14 天后进行的诺伍德手术死亡率很高。我们分析了晚期诺伍德手术的实际风险以及影响死亡率的其他因素:对 2019 年 1 月至 2023 年 12 月期间接受诺伍德手术的一系列连续患者进行单中心回顾性研究。考虑了患者的特征,以确定与院内和阶段间死亡率相关的因素:共纳入 35 名患者,71%(25 人)的患者在出生 14 天后接受了诺伍德手术。中位年龄为 27 天(6-259 天)。院内死亡率为 26%(9/35),其中 89%(8)的死者在手术时年龄超过 15 天。对手术结果产生负面影响的其他因素包括:66%的患者(23例)存在限制性房间隔缺损(ASD),46%的患者(16例)需要机械通气,43%的患者(15例)在手术前出现全身感染:诺伍德手术时的年龄与较高的死亡风险无关,但限制性房间隔缺损、术前感染和术前需要机械通气等其他因素对预测短期结果更为重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
In-Hospital and Interstage Mortality After Late Norwood Procedure: Acknowledging the Risks When We Are Running Out of Time.

Background: A Norwood procedure performed after 14 days of life is notably burdened by a high mortality. We analysed the real risk and which other factors influence the mortality in late Norwood procedures.

Methods: A single-centre, retrospective review of a series of consecutive patients who underwent a surgical Norwood procedure from January 2019 until December 2023. The patients' characteristics were considered to identify the factors associated with in-hospital and interstage mortality.

Results: 35 patients were included and 71% (25) of the patients underwent the Norwood procedure after 14 days of life. The median age was 27 days (6-259 days). The in-hospital mortality was 26% (9/35) with 89% (8) of the deceased being older than 15 days at the time of the surgery. Other factors that negatively affected the outcome were a restrictive interatrial septum defect (ASD) in 66% of all patients (23), the need for mechanical ventilation in 46% (16) and systemic infection prior to surgery in 43% (15).

Conclusions: Age at the time of Norwood was not associated with a higher risk of mortality, but other factors such as restrictive ASD, preoperative infection and the need for mechanical ventilation prior to surgery are even more important in predicting the short-term outcome.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Children-Basel
Children-Basel PEDIATRICS-
CiteScore
2.70
自引率
16.70%
发文量
1735
审稿时长
6 weeks
期刊介绍: Children is an international, open access journal dedicated to a streamlined, yet scientifically rigorous, dissemination of peer-reviewed science related to childhood health and disease in developed and developing countries. The publication focuses on sharing clinical, epidemiological and translational science relevant to children’s health. Moreover, the primary goals of the publication are to highlight under‑represented pediatric disciplines, to emphasize interdisciplinary research and to disseminate advances in knowledge in global child health. In addition to original research, the journal publishes expert editorials and commentaries, clinical case reports, and insightful communications reflecting the latest developments in pediatric medicine. By publishing meritorious articles as soon as the editorial review process is completed, rather than at predefined intervals, Children also permits rapid open access sharing of new information, allowing us to reach the broadest audience in the most expedient fashion.
期刊最新文献
Decoding Apelin: Its Role in Metabolic Programming, Fetal Growth, and Gestational Complications. Development and Validation of a Diagnostic Algorithm for Down Syndrome Using Birth Certificate and International Classification of Diseases Codes. Parenting in the Face of Trauma: Music Therapy to Support Parent-Child Dyads Affected by War and Displacement. Conducting Patient-Oriented Research in Pediatric Populations: A Narrative Review. Digital Narratives: The Impact of Instagram® on Mothers of Children with Congenital Toxoplasmosis.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1