先天性巨细胞病毒感染儿童的听力和前庭随访:从目前的局限到未来的方向。

IF 2 4区 医学 Q2 PEDIATRICS Children-Basel Pub Date : 2024-10-01 DOI:10.3390/children11101211
Mirko Aldè, Virginia Fancello, Paola Di Mauro, Rachele Canelli, Sandra Zaouche, Chiara Falanga
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引用次数: 0

摘要

目前,先天性巨细胞病毒(CMV)患儿的听力和前庭随访指南尚不明确。一般建议是在相同的时间间隔内对所有先天性巨细胞病毒患儿的听力进行评估:1 岁前每 3-6 个月评估一次,1-3 岁每 6 个月评估一次,3-6 岁每年评估一次。此外,对于先天性巨细胞病毒(CMV)患儿的前庭随访,虽然有时会使用视频头脉冲测试(v-HIT)和颈前庭诱发肌源性电位(cVEMPs),但目前还没有公认的方案。这篇叙述性综述对先天性巨细胞病毒患儿现有的听力和前庭随访方法进行了严格评估,强调了个性化方案的必要性。根据风险因素(如母体感染的三个月、羊水中 CMV PCR 结果、缬更昔洛韦的使用情况等)定制不同时间和方法的随访计划,确实能让评估更精确、干预更及时、资源分配更优化。这一策略还将减轻家庭的后勤和情感负担,确保高风险儿童接受更频繁、更适当的评估和早期干预,而低风险儿童则避免不必要的检测。
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Audiological and Vestibular Follow-Up for Children with Congenital Cytomegalovirus Infection: From Current Limitations to Future Directions.

Currently, the guidelines for audiological and vestibular follow-up in children with congenital cytomegalovirus (CMV) are not well-defined. The general recommendation is to evaluate hearing in all children with congenital CMV at the same intervals: once every 3-6 months up to 1 year of age, once every 6 months from 1 to 3 years of age, and once a year from 3 to 6 years of age. Additionally, there are no universally accepted protocols for the vestibular follow-up of children with congenital CMV, although video head impulse test (v-HIT) and cervical vestibular-evoked myogenic potentials (cVEMPs) are sometimes used. This narrative review critically evaluates existing audiological and vestibular follow-up approaches for children with congenital CMV, highlighting the need for personalized protocols. Tailoring follow-up schedules with different timing and methods based on risk factors, such as the trimester of maternal infection, CMV PCR results in amniotic fluid, and valganciclovir use, would indeed allow for more precise evaluations, timely interventions, and optimized resource allocation. This strategy would also alleviate the logistical and emotional burdens on families by ensuring that high-risk children receive more frequent and appropriate assessments and early interventions, while lower-risk children avoid unnecessary testing.

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来源期刊
Children-Basel
Children-Basel PEDIATRICS-
CiteScore
2.70
自引率
16.70%
发文量
1735
审稿时长
6 weeks
期刊介绍: Children is an international, open access journal dedicated to a streamlined, yet scientifically rigorous, dissemination of peer-reviewed science related to childhood health and disease in developed and developing countries. The publication focuses on sharing clinical, epidemiological and translational science relevant to children’s health. Moreover, the primary goals of the publication are to highlight under‑represented pediatric disciplines, to emphasize interdisciplinary research and to disseminate advances in knowledge in global child health. In addition to original research, the journal publishes expert editorials and commentaries, clinical case reports, and insightful communications reflecting the latest developments in pediatric medicine. By publishing meritorious articles as soon as the editorial review process is completed, rather than at predefined intervals, Children also permits rapid open access sharing of new information, allowing us to reach the broadest audience in the most expedient fashion.
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