癌症治疗、诊断和管理中的纳米技术。

Biotechnologia Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI:10.5114/bta.2024.141807
Disha Hazarika, Sumit Sarma, Priyanka Shankarishan
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引用次数: 0

摘要

纳米技术在治疗、诊断和管理方面取得了重大进展,为癌症研究带来了令人振奋的机遇。由于纳米技术具有在分子水平操纵物质的独特能力,它在提高癌症治疗的准确性和有效性,同时减少不良反应方面具有无与伦比的潜力。使用纳米粒子载体有助于通过定制的给药系统将治疗药物精确地输送到人体内的患病部位,从而提高治疗的准确性和有效性,同时减少不良反应。这些技术提高了药物的溶解度和稳定性,从而提高了生化可用性水平,改善了患者的疗效,并将治疗周期中的负面影响降至最低。纳米粒子的另一个用途包括肿瘤成像;纳米粒子与含有诊断剂的靶向配体功能化,可促进早期检测,使更快的补救行动计划成为可能。总之,纳米技术的应用前景广阔,但在广泛临床应用之前,还需要解决监管障碍和安全问题。尽管癌症研究和病人护理工作十分复杂,但纳米技术有望改变这两个领域。
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Nanotechnology in cancer therapeutics, diagnosis, and management.

Nanotechnology presents an exciting opportunity in cancer research by offering significant advancements in therapies, diagnosis, and management. It possesses unparalleled potential to enhance the accuracy and effectiveness of cancer therapy while simultaneously reducing adverse effects, owing to its distinctive capability to manipulate matter at a molecular level. Using nanoparticle carriers has facilitated the precise administration of therapeutic agents to afflicted areas within the human body through customized drug delivery systems, resulting in improved treatment accuracy and efficacy while reducing adverse effects. These techniques improve drug solubility and stability, leading to elevated levels of biochemical availability and improved efficacy outcomes for patients with minimal negative effects during treatment cycles. Another use case for nanoparticles includes tumor imaging; functionalized with targeting ligands containing diagnostic agents, they foster early detection, making quicker remedial action plans possible. Overall, the incorporation of nanotechnology ensures a promising future, although it stresses the need to address regulatory hurdles and safety concerns before widespread clinical implementation. Despite the complexity of cancer research and patient care, nanotechnology shows promise in transforming both fields.

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