冠状动脉钙化评分对猝死病例放射学和自体检查结果的预测价值

IF 0.8 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Forensic Imaging Pub Date : 2024-10-22 DOI:10.1016/j.fri.2024.200610
Jessika Camatti , Anna Laura Santunione , Stefano Draisci , Drago Antonella , Maria Grazia Amorico , Guido Ligabue , Enrico Silingardi , Pietro Torricelli , Rossana Cecchi
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引用次数: 0

摘要

冠状动脉钙化评分(CACS)是通过心脏计算机断层扫描计算冠状动脉钙化量的一种无创检查。近年来,尸检成像在猝死中的作用越来越受到关注,之前的研究提出了 CACS 与尸检结果之间可能存在的相关性。本研究旨在建立CACS、多相死后计算机断层扫描血管成像(MPMCTA)中出现的冠状动脉不透明缺陷与尸检时出现的冠状动脉狭窄之间的相关性,以验证CACS是否证实了其在心脏风险方面的预测价值,并能指导是否进行MPMCTA的决定。首先进行 MPMCTA,然后进行尸检。对 24 名死者(53 岁 ± 11.7;20 名男性)进行了评估。在评估是否存在放射学冠状动脉不透明缺陷方面,CACS 的阳性预测值为 0.78,阴性预测值为 0.73。在评估猝死病例时,CACS 是一个合适的补充工具。我们的研究结果为在猝死病例中系统应用 CACS 做出了令人鼓舞的贡献。
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Predictive value of coronary artery calcium score on radiological and autoptic findings in cases of sudden death
Calcium Artery Coronary Score (CACS) is a noninvasive examination of the coronary arteries in which the amount of calcium is calculated using cardiac Computed Tomography. The role of postmortem imaging in sudden death has been the subject of increasing interest in recent years, and previous studies have proposed a possible correlation between CACS and autopsy findings.
The present study aims to establish a correlation between CACS, the presence of coronary artery opacification defects on Multi-Phase Post-Mortem Computed Tomography Angiography (MPMCTA), and the presence of coronary stenosis at autopsy, in order to verify whether CACS confirms its predictive value in terms of cardiac risk and can guide the decision to perform or not to perform MPMCTA.
A cohort of 24 subjects who died suddenly was examined. Firstly, MPMCTA was performed, then autopsy was carried out. CACS was calculated, the detection of opacification defects on MPMCTA was investigated and the presence of coronary stenoses on autopsy was described.
24 deceased individuals (53 years ± 11.7; 20 men) were evaluated. CACS has a positive predictive value of 0.78 and a negative predictive value of 0.73 in assessing the presence of radiological coronary artery opacification defects. The positive predictive value on stenosis relief is 0.88, while the negative predictive value on the same relief is 0.73.
CACS is an appropriate additional tool in the evaluation of sudden death cases. Our results provided an encouraging contribution to the systematic application of CACS in cases of sudden death.
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来源期刊
Forensic Imaging
Forensic Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.20
自引率
27.30%
发文量
39
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