模型和健康志愿者的水脂磁共振成像的准确性、可重复性和再现性

Anouk Corbeau , Pien van Gastel , Piotr A. Wielopolski , Nick de Jong , Carien L. Creutzberg , Uulke A. van der Heide , Stephanie M. de Boer , Eleftheria Astreinidou
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引用次数: 0

摘要

化放疗导致的骨髓(BM)损伤会增加宫颈癌患者的骨髓脂肪。为了验证质子密度脂肪分数的准确性、可重复性以及在不同供应商、场强和方案下的可重复性,我们在一个模型和一名健康女性志愿者身上进行了水脂肪磁共振(MR)扫描。模型测量结果显示了高准确性、高重复性和出色的再现性。志愿者的测量结果在读取器内部和读取器之间具有极佳的可靠性、良好的可重复性和中等至良好的再现性。水脂磁共振成像显示出量化椎体基质脂肪纵向变化的潜力。还需要进一步的研究来验证和扩展这些发现的临床适用性。
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Accuracy, repeatability, and reproducibility of water-fat magnetic resonance imaging in a phantom and healthy volunteer
Bone marrow (BM) damage due to chemoradiotherapy can increase BM fat in cervical cancer patients. Water-fat magnetic resonance (MR) scans were performed on a phantom and a healthy female volunteer to validate proton density fat fraction accuracy, reproducibility, and repeatability across different vendors, field strengths, and protocols. Phantom measurements showed a high accuracy, high repeatability, and excellent reproducibility. Volunteer measurements had an excellent intra- and interreader reliability, good repeatability, and moderate to good reproducibility. Water-fat MRI show potential for quantification of longitudinal vertebral BM fat changes. Further studies are needed to validate and extend these findings for broader clinical applicability.
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来源期刊
Physics and Imaging in Radiation Oncology
Physics and Imaging in Radiation Oncology Physics and Astronomy-Radiation
CiteScore
5.30
自引率
18.90%
发文量
93
审稿时长
6 weeks
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