利用 DLW 方法制作用于细胞研究的笼状微支架

IF 2.5 3区物理与天体物理 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Photonics and Nanostructures-Fundamentals and Applications Pub Date : 2024-10-11 DOI:10.1016/j.photonics.2024.101321

A.V. Pisarenko , D.S. Burkatovskii , D.A. Kolymagin , D.A. Chubich , V.I. Borshchevskiy , A.G. Vitukhnovsky

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引用次数: 0

摘要

本文重点介绍了利用激光直接写入法制造仿细胞外基质的三维生物兼容支架的方法。本文详细探讨了 HEK 293 细胞与这些笼状支架之间的相互作用，特别是孔径对细胞侵袭的影响。我们的研究强调了支架结构对细胞行为的影响，并突出了直接激光写入技术在创建复杂三维支架方面的潜力。从这项研究中获得的洞察力在未来的组织工程、再生医学和药物输送等应用中可能非常有价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cage-like micro-scaffolds fabricated by DLW method for cell investigation

This paper focuses on the use of direct laser writing method in fabricating three-dimensional biocompatible scaffolds that emulate the extracellular matrix. The interaction between HEK 293 cells and these cage-like scaffolds, particularly the effect of pore size on cell invasion, is explored in detail. Our study underscores the influence of scaffold architecture on cellular behavior and highlights the potential of direct laser writing technology in creating complex 3D scaffolds. The insights gleaned from this research could be invaluable in future applications such as tissue engineering, regenerative medicine, and drug delivery.

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来源期刊

Photonics and Nanostructures-Fundamentals and Applications 工程技术-材料科学：综合

CiteScore

5.00

自引率

3.70%

发文量

审稿时长

62 days

期刊介绍： This journal establishes a dedicated channel for physicists, material scientists, chemists, engineers and computer scientists who are interested in photonics and nanostructures, and especially in research related to photonic crystals, photonic band gaps and metamaterials. The Journal sheds light on the latest developments in this growing field of science that will see the emergence of faster telecommunications and ultimately computers that use light instead of electrons to connect components.