Reaction of 6-Methylpyridin-2-ylphosphine with Benzaldehyde and p-Toluidine: A Pathway to Acyclic Aminomethylphosphine Oxides with Carbon-Substituted PCHN Fragments

The reaction of 6-methylpyridin-2-ylphosphine with benzaldehyde and p-toluidine was investigated. This reaction leads to the formation of three isomers of acyclic aminomethylphosphine oxide with a moderate yield. The structures of the compounds were confirmed by NMR and IR spectroscopy data. It was shown that the reaction results in the formation of three isomers of acyclic aminomethylphosphine. One of the isomers was isolated in a crystalline form suitable for the single crystal X-ray diffraction analysis. According to the XRD data, the isomer is crystallized as dimers formed by N–H···O hydrogen bonds.