用于牙科应用的具有仿生分级设计的氧化锆/树脂复合材料的数字光打印。

IF 4.6 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Dental Materials Pub Date : 2024-10-28 DOI:10.1016/j.dental.2024.10.010
Qiuyi Li, Yongzhe Liu, Delu Zhao, Yupu Yang, Qibo Liu, Yujun Zhang, Junling Wu, Zheqin Dong
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引用次数: 0

摘要

目的:应力集中和对颌牙过度磨损是导致全瓷冠修复失败的主要问题。本研究的目的是(1) 合成仿生物梯度氧化锆/树脂复合材料。(2)控制孔隙率和结构,使仿生梯度氧化锆/树脂复合材料的机械性能接近牙釉质和牙本质:方法:使用3DMax和Magics设计了不同宽度(1.6毫米、1.8毫米、1.9毫米、2.0毫米、2.2毫米)的仿生均匀氧化锆支架和仿生梯度(1.6毫米-2.2毫米)氧化锆支架,通过数字光处理3D打印制作了支架,然后将其渗入牙科树脂中进行力学测试、有限元模拟和细胞毒性测试:结果表明,与氧化锆陶瓷支架相比,陶瓷-聚合物复合材料的强度(增加 1.37 倍)和韧性(增加 2.08 倍)均有显著提高(P 结论:陶瓷-聚合物复合材料的强度和韧性与氧化锆陶瓷支架相比均有显著提高(P 结论:与氧化锆陶瓷支架相比,陶瓷-聚合物复合材料的强度和韧性均有显著提高(P 结论):通过一系列研究,精确制备了仿生梯度氧化锆/牙科树脂材料,有望进一步提高临床治疗效果。同时,这种策略性设计也为其他牙科材料的性能改进提供了新思路:意义:精确制备了具有与天然牙齿相匹配的机械性能的梯度氧化锆/树脂复合材料,有望显著改善临床治疗效果。此外,该战略设计还为提高其他牙科材料的性能提供了新的思路。
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Digital light printing of zirconia/resin composite material with biomimetic graded design for dental application.

Objective: Stress concentration and excessive wear on the opposite jaw teeth are the main problems that lead to the failure of all-ceramic crown restoration. The objectives of this study were to: (1) Synthesize the biomimetic gradient zirconia/resin composites. (2) Control the porosity and structure so that the mechanical properties of the biomimetic gradient zirconia/resin composites are close to enamel and dentin.

Methods: Biomimetic uniform zirconia scaffolds with different widths (1.6 mm, 1.8 mm, 1.9 mm, 2.0 mm, 2.2 mm) and Biomimetic gradient (1.6 mm-2.2 mm) zirconia scaffolds were designed using 3DMax and Magics, fabricated by digital light processing 3D printing, and then infiltrated into dental resin for mechanical testing, finite element simulation and cytotoxicity testing.

Results: Results show that the ceramic-polymer composites exhibit a significant enhancement in strength (1.37-fold increase) and toughness (2.08-fold increase) compared to zirconia ceramic scaffold (P < 0.05), highlighting the effectiveness of our structural design. In addition, the gradient design further improves the mechanical strength of the composites. Notably, the gradient composite crown exhibits a bending strength of 138.3 (±16.7) MPa, a toughness of 9.0 (±0.5) MJ/m³, and a compressive strength of 113.7 (±2.6) MPa, values that are comparable to those of natural enamel and dentin, and shows good biosafety.

Conclusion: Biomimetic gradient zirconia/dental resin materials were precisely fabricated through a series of studies, which is expected to further improve the clinical treatment effect. At the same time, the strategic design also provides new ideas for the performance improvement of other dental materials.

Significance: Gradient zirconia/resin composite materials with mechanical properties matching natural teeth were precisely fabricated, and are expected to significantly improve clinical treatment outcomes. Additionally, the strategic design provides new insights for enhancing the performance of other dental materials.

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来源期刊
Dental Materials
Dental Materials 工程技术-材料科学:生物材料
CiteScore
9.80
自引率
10.00%
发文量
290
审稿时长
67 days
期刊介绍: Dental Materials publishes original research, review articles, and short communications. Academy of Dental Materials members click here to register for free access to Dental Materials online. The principal aim of Dental Materials is to promote rapid communication of scientific information between academia, industry, and the dental practitioner. Original Manuscripts on clinical and laboratory research of basic and applied character which focus on the properties or performance of dental materials or the reaction of host tissues to materials are given priority publication. Other acceptable topics include application technology in clinical dentistry and dental laboratory technology. Comprehensive reviews and editorial commentaries on pertinent subjects will be considered.
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