智能压力控制输尿管镜联合铥激光治疗孤立性上尿路尿路上皮癌的临床疗效分析。

IF 3.5 3区 医学 Q2 ONCOLOGY Frontiers in Oncology Pub Date : 2024-10-15 eCollection Date: 2024-01-01 DOI:10.3389/fonc.2024.1406031
Hua Chen, Jiansheng Xiao, Jiaqi Ge, Tairong Liu
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引用次数: 0

摘要

目的:探讨智能压控输尿管镜联合铥激光治疗孤立肾上尿路癌(UTUC)患者的临床治疗效果:方法:该研究旨在探讨智能压控输尿管镜联合铥激光治疗孤立肾上尿路上皮癌(UTUC)患者的临床治疗效果:本研究采用回顾性分析方法,以我院2018年6月-2023年5月收治的6例孤立肾UTUC患者为研究对象,采用智能压控输尿管镜联合铥激光进行肿瘤切除手术。我们收集了这6例患者的围手术期临床资料,并对治疗效果进行了统计分析:结果:六名患者的手术均顺利完成,未出现因大出血而终止手术的情况。术后病理结果显示,4 例患者为低分化非浸润性乳头状尿路上皮癌,另外 2 例患者为高分化浸润性尿路上皮癌。随访期间,一名患者在术后三个月出现肾盂复发,随后接受了铥激光切除术。此外,另一名患者在术后八个月出现膀胱复发,接受了经尿道膀胱肿瘤切除术(TURBT)治疗。其余四名患者在随访期间均未出现肿瘤复发:结论:对于伴有UTUC的孤立肾患者,智能压力控制输尿管镜联合铥激光是一种可行的治疗方案,对低风险上尿路上皮癌具有良好的治疗效果。
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Clinical efficacy analysis of intelligent pressure-controlled ureteroscopy combined with thulium laser in the treatment of isolated upper urinary tract urothelial carcinoma.

Objective: This study aims to investigate the clinical treatment effect of intelligent pressure-controlled ureteroscopy combined with thulium laser for patients with isolated kidney upper tract urothelial carcinoma (UTUC).

Methods: This study employed a retrospective analysis approach and focused on six patients with isolated kidney UTUC admitted to our hospital from June 2018 to May 2023, who underwent tumor resection surgery using intelligent pressure-controlled ureteroscopy combined with thulium laser. We collected the perioperative clinical data of these six patients and conducted statistical analysis of the treatment effects.

Results: The surgeries of all six patients were completed smoothly, without incidents of surgery termination due to significant bleeding. Postoperative pathology revealed that four patients had low-grade non-invasive papillary urothelial carcinoma, while the other two patients had high-grade invasive urothelial carcinoma. During follow-up period, one patient had a renal pelvis recurrence three months after the surgery, and subsequently underwent thulium laser resection. Additionally, another patient experienced bladder recurrence eight months after the surgery and received transurethral resection of bladder tumor (TURBT) for treatment. The remaining four patients did not experience tumor recurrence during the follow-up.

Conclusion: For patients with isolated kidney associated with UTUC, intelligent pressure-controlled ureteroscopy combined with thulium laser represents a feasible treatment option, with good therapeutic effects for low-risk upper tract urothelial carcinoma.

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来源期刊
Frontiers in Oncology
Frontiers in Oncology Biochemistry, Genetics and Molecular Biology-Cancer Research
CiteScore
6.20
自引率
10.60%
发文量
6641
审稿时长
14 weeks
期刊介绍: Cancer Imaging and Diagnosis is dedicated to the publication of results from clinical and research studies applied to cancer diagnosis and treatment. The section aims to publish studies from the entire field of cancer imaging: results from routine use of clinical imaging in both radiology and nuclear medicine, results from clinical trials, experimental molecular imaging in humans and small animals, research on new contrast agents in CT, MRI, ultrasound, publication of new technical applications and processing algorithms to improve the standardization of quantitative imaging and image guided interventions for the diagnosis and treatment of cancer.
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