RAC-OST-POL 研究中的跌倒:10 年前瞻性纵向观察结果。

Wojciech Pluskiewicz, Piotr Adamczyk, Bogna Drozdzowska
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摘要

简介材料与方法:研究对象包括 640 名年龄在 55 岁以上的绝经后妇女。材料和方法:共纳入了 640 名绝经后妇女,她们的基线年龄都在 55 岁以上,组群是从整个拉齐博尔兹地区的人口中随机抽取的。结果:256 名妇女(40%)没有摔倒过,384 名妇女(60%)至少摔倒过一次。跌倒 1 次、2 次和 3 次或 3 次以上的女性人数分别为 115 人、62 人和 207 人。跌倒总人数为 1988 人。注意到跌倒的女性的平均基线年龄为 65.7 ± 7.02 岁,明显高于其他患者(64.1 ± 6.75;p 结论:在对绝经后妇女的长期随访中,经常观察到跌倒现象,而跌倒会增加骨折率。1 型糖尿病和抑郁症会增加跌倒率,这表明有必要采取一些预防措施。
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Falls in RAC-OST-POL Study: the results from 10-year prospective longitudinal observation.

Introduction: The aim of the study was presentation of the data on falls in a cohort of postmenopausal women in a 10-year prospective longitudinal observation.

Material and methods: 640 postmenopausal women at baseline age above 55 years were included. The cohort was randomly selected from the population of the whole Racibórz district. Data on falls and fracture incidence were gathered yearly.

Results: 256 (40%) women had no falls, and in 384 (60%) subjects at least one fall was noted. The number of women with 1, 2, and 3 or more falls were 115, 62, and 207, respectively. The total number of falls was 1988. Mean baseline age in those who noted falls was 65.7 ± 7.02 years, and it was significantly higher than in the rest of the patients (64.1 ± 6.75; p<0.01). During follow-up 190 osteoporotic fractures were noted in 129 patients. Falls were proven to have a strong, significant relationship with fracture (chi-square test = 80.5; p < 0.0001). Among potential clinical factors only diabetes type 1 (chi-square test = 5.80; p < 0.05) and depression (chi-square test = 3.82; p < 0.05) influenced falls incidence. The risk of falls was increased in cases of greater numbers of clinical risk factors (chi-square test = 28.4 df = 5; p < 0.0001).

Conclusions: In long-term follow-up in postmenopausal women, falls were frequently observed, and their occurrence increased the fracture rate. Diabetes type 1 and depression increase the fall rate, which suggests the necessity of implementation of some preventive procedures.

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