The therapeutic perspective of cinnamon (Cinnamomum verum) consumption against metabolic syndrome

Metabolic syndrome (MetS) is one of the most significant worldwide public health issues. Hypertension, visceral obesity, hyperglycemia, dyslipidemia, and insulin resistance are some of the contributing variables. The latest MetS preventative measures have focused on lifestyle factors and combination therapy, including exercise and herbal treatment. Cinnamon (Cinnamomum verum) is rich in phytochemicals, including phenolic and volatile compounds, responsible for its antitumor, anticancer, antidiabetic, and anti-hypertriglyceridemia potentials. Numerous clinical studies have demonstrated the value of cinnamon’s anti-inflammatory properties in treating diabetes. Cinnamon is crucial in maintaining normal levels of lipids in the blood. In the past ten years, several clinical studies have examined the effectiveness of cinnamon administration in managing inflammation-related diseases, metabolic abnormalities, and polycystic ovarian syndrome. Comprehensive information about the chemical composition, nutritional compounds, phytoconstituents, and protective role of cinnamon and cinnamaldehyde against metabolic syndrome has been presented in this review. An effort has also been made to explain the mechanisms of blood glucose management, visceral obesity management, and cinnamon safety and toxicity aspects.