胸主动脉血管内修复术中的主动脉扩大覆盖与脊髓缺血无关

George C. Chachati MD , Sarah Yousef MD , James A. Brown MD , Nishant Agrawal , Shwetabh Tarun , Kristian Punu , Derek Serna-Gallegos MD, FACS , Julie Phillippi PhD , Ibrahim Sultan MD
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引用次数: 0

摘要

目的胸腔内血管主动脉修复术(TEVAR)后脊髓缺血(SCI)仍是一种使人衰弱的并发症,10% 的患者会出现这种情况。研究表明,延长主动脉覆盖范围是导致 SCI 的一个风险因素。本研究评估了主动脉长度延长覆盖是否是 SCI 的重要风险因素。方法本研究回顾性分析了 2006 年至 2021 年期间在一家机构成功接受 TEVAR 的 277 例连续患者。患者被分为两组:胸主动脉覆盖范围≥205 mm和<205 mm。方差分析用于比较两组之间的这些变量和相关的主动脉覆盖情况。结果 在成功接受 TEVAR 的 269 例患者中,127 例(47.2%)的主动脉覆盖范围≥205 mm,142 例(52.8%)的主动脉覆盖范围为 <205 mm。胸主动脉覆盖范围≥205 毫米的患者更有可能是吸烟者(P < .01)和既往有中风史者(P < .05)。覆盖范围扩大的患者更有可能在术前接受腰椎引流管(LD)治疗(P < .01)。与标准主动脉覆盖相比,扩大主动脉覆盖与较高的 SCI 风险无关(4.7% vs 4.2%; P = .84)。有无术前 LD 的主动脉扩大覆盖与 SCI 无关(P = .91)。结论扩大主动脉覆盖(与标准方法相比)与较高的 SCI 风险无关;但是,在该人群中,预防性腰椎引流的发生率较高,这可能会减轻 SCI 的风险。
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Extended aortic coverage in thoracic aortic endovascular repair is not associated with spinal cord ischemia

Objective

Spinal cord ischemia (SCI) after thoracic endovascular aortic repair (TEVAR) remains a debilitating complication, occurring in 10% of patients. Studies have shown that extended aortic coverage is a risk factor for SCI. This study evaluates whether extended aortic length coverage is a significant risk factor for SCI.

Methods

This study retrospectively reviewed 277 consecutive patients who underwent TEVAR successfully between 2006 and 2021 at a single institution. The patients were classified into 2 groups: ≥205 mm and <205 mm of thoracic aortic coverage. Analysis of variance was used to compare these variables and associated aortic coverage between the 2 groups. Univariable logistical regression was used to compare SCI and associated factors.

Results

Of the 269 patients who underwent successful TEVAR, 127 (47.2%) had ≥205 mm and 142 (52.8%) had <205 mm of aorta coverage. Patients with ≥205 mm of thoracic aorta coverage were more likely to be smokers (P < .01) and to have a history of previous stroke (P < .05). Patients with extended coverage were more likely to receive a preoperative lumbar drain (LD) (P < .01). Extended aortic coverage was not associated with a higher risk of SCI compared to standard aortic coverage (4.7% vs 4.2%; P = .84). Extended aortic coverage with or without a preoperative LD did not have an association with SCI (P = .91). Type II endoleaks were seen more in extended aortic coverage (P < .01).

Conclusions

Extended aortic coverage (compared with the standard approach) was not associated with a higher risk of SCI; however, this may have been mitigated by a higher prevalence of prophylactic lumbar drainage in this population.
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