肝化疗栓塞期间职业暴露的计算评估

IF 2.8 3区 物理与天体物理 Q3 CHEMISTRY, PHYSICAL Radiation Physics and Chemistry Pub Date : 2024-10-18 DOI:10.1016/j.radphyschem.2024.112296
Thays Maria P. Machado , Monique F. Silva , Evelyn L. de Oliveira , Isabella P. Tobias , William S. Santos , Lucio P. Neves , Ana P. Perini
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引用次数: 0

摘要

经动脉化疗栓塞术(TACE)是治疗肝细胞癌(HCC)的替代方法之一。在这一过程中,职业暴露者(OEIs)会留在室内,因此会受到辐射。这项工作的目的是评估 OEI 在 HCC TACE 过程中接受的等效和有效剂量。评估是通过等效剂量(CC[HT])和有效剂量(CC[E])的转换系数进行的。这项研究是在计算机模拟的基础上进行的,使用的是蒙特卡罗 N 粒子代码 6.2 版。建立的介入放射学(IR)室包含 3 个男性虚拟模型(MASH3),分别代表主治医生、助手和病人。场景根据后正位(PA)、头颅 12°(CRA12)、尾椎 12°(CAU12)和左前斜 26°(LAO26)投影以及不同的管电压值(70 和 80 kV)而有所不同,视野大小固定为 35 × 35 平方厘米。此外,还将个人防护设备(PPE)和集体防护设备(CPE)纳入方案中,以评估 OIE 的剂量降低情况。结果表明,当使用 80 kV 管电压时,OEI 收到的最高剂量值是 LAO26 投影。使用个人防护设备后,主治医生的 CC[E]值减少了 95%,CC[HT]值减少了 99%。在不使用个人防护设备的情况下,主治医师收到的绝对有效剂量为 266.71 μSv,助手收到的绝对有效剂量为 30.29 μSv。在使用所有个人防护设备和个人防护装备后,这些专业人员的有效剂量降低到 24.12 μSv (主治医师)和 1.16 μSv (助理医师)。使用防护设备可大幅降低剂量,这凸显了坚持使用这些设备的极端重要性。
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Computational assessment of occupational exposure during hepatic chemoembolization
One of the treatment alternatives for hepatocellular carcinoma (HCC) is transarterial chemoembolization (TACE). During this procedure, occupationally exposed individuals (OEIs) remain in the room and, therefore, are exposed to radiation. The objective of this work was to evaluate the equivalent and effective doses that OEIs received from TACE procedure of HCC. The evaluation was carried out by means of conversion coefficients for equivalent (CC[HT]) and effective (CC[E]) doses. The study was conducted based on computer simulation, using the Monte Carlo N-Particle code, version 6.2. An interventional radiology (IR) room was built containing 3 male virtual phantoms (MASH3) to represent the main physician, the assistant, and the patient. The scenarios varied according to the posteroanterior (PA), cranial, 12° (CRA12), caudal, 12° (CAU12) and left anterior oblique, 26° (LAO26) projections and different tube voltage values (70 and 80 kV) with the field size fixed at 35 × 35 cm2. Furthermore, personal protective equipment (PPE) and collective protective equipment (CPE) were incorporated into the scenarios to evaluate the dose reduction on the OIEs. It was observed that the highest dose values received by the OEIs were for the LAO26 projection when an 80 kV tube voltage was applied. The CC[E] values were reduced by up to 95%, while the CC[HT] values saw a reduction of up to 99% with the use of PPEs, for the main physician. Considering the scenario without the use of PPEs, the absolute effective dose received by the main physician was 266.71 μSv and by the assistant 30.29 μSv. When all PPEs and CPEs were used, the effective doses for these professionals were reduced to 24.12 μSv (main physician) and 1.16 μSv (assistant). The significant dose reduction achieved with protective equipment underscores the critical importance of consistently using these devices.
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来源期刊
Radiation Physics and Chemistry
Radiation Physics and Chemistry 化学-核科学技术
CiteScore
5.60
自引率
17.20%
发文量
574
审稿时长
12 weeks
期刊介绍: Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.
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