Evaluation of excitation functions of 127I(p,xn) 121,122, 123, 125,127Xe reactions, with particular reference to the production of 127Xe and 123I for medical use

Cross section data for the formation of ^{121,122,123,125,127}Xe via proton induced reactions on ¹²⁷I were critically analyzed. Three nuclear model codes (TALYS 1.9, ALICE-IPPE, and EMPIRE 3.2) were used to ensure the consistency and reliability of the experimental data. Utilizing a well-developed evaluation methodology, a recommended fit for each excitation function was obtained, based on theoretical predictions of nuclear models and experimental cross sections. By using the recommended/reference results, thick target yields were calculated for each production route and its associated impurity reactions. The indirect production of the radionuclides ^{121,122,123,125}I was explored. Special attention was paid to standardization of cross section data for the production of the medically important radionuclides ¹²⁷Xe and ¹²³I via the routes ¹²⁷I(p,n)¹²⁷Xe and ¹²⁷I(p,5n)¹²³Xe(EC, β+)¹²³I, respectively.