二级医疗中心儿科病房抗生素处方模式:基于世界卫生组织 AWaRe 分类的回顾性研究。

IF 1.4 Q3 PEDIATRICS Global Pediatric Health Pub Date : 2024-10-22 eCollection Date: 2024-01-01 DOI:10.1177/2333794X241291409
Afia Tariq Butt, Sobia Ramzan, Dania Shabbir, Amna Sajjad, Murk Shaikh, Maryam Iqbal Syed, Mohammad Aadil Qamar
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引用次数: 0

摘要

目的。抗菌药耐药性(AMR)对全球公共卫生构成了重大威胁,与 AMR 相关的感染导致了大量死亡。由于普遍滥用抗菌药物,儿科人群面临着更大的脆弱性。本研究旨在应对抗菌药耐药性(AMR)及其相关死亡率的重大威胁。方法。这项回顾性横断面多中心研究调查了阿迦汗大学医院下属 4 家二级医院儿科病房的抗生素处方模式。研究采用了世界卫生组织的 "获取、观察和储备"(AWaRe)分类框架。对 6934 次就诊的数据进行了分析。研究结果78.1%的病例开具了抗生素处方,其中以静脉注射为主(98.6%)。头孢曲松是处方量最多的抗生素(45.8%),第三代头孢菌素是最常用的抗生素类别(54.4%)。肺炎的处方率最高(99.9%),各家医院主要处方的是观察组抗生素(>80%)。结论这些研究结果表明,当务之急是采取有针对性的干预措施,以优化处方做法并减少耐药性。
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Prescribing Patterns of Antibiotics in Pediatric Wards of Secondary Care Centers: A Retrospective Study Based on WHO AWaRe Classification.

Objectives. Antimicrobial resistance (AMR) poses a significant threat to global public health, with substantial mortality rates attributed to AMR-related infections. Pediatric populations face heightened vulnerability due to prevalent antimicrobial misuse. This study aimed at addressing the significant threat of antimicrobial resistance (AMR) and its associated mortality rates. Methods. This retrospective cross-sectional multicentric study investigated antibiotic prescribing patterns in pediatric wards of 4 secondary care hospitals affiliated with Aga Khan University Hospital. The study utilized the WHO Access, Watch, and Reserve (AWaRe) classification framework. Data from 6934 encounters were analyzed. Results. Antibiotics were prescribed in 78.1% of encounters, with intravenous administration being predominant (98.6%). Ceftriaxone was the most prescribed antibiotic agent (45.8%), and third-generation cephalosporins constituted the most prevalent antibiotic class (54.4%). Pneumonia exhibited the highest prescription rate (99.9%), with Watch group antibiotics being predominantly prescribed (>80%) across hospitals. Conclusion. These findings underscore the urgency for targeted interventions to optimize prescribing practices and mitigate resistance.

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来源期刊
Global Pediatric Health
Global Pediatric Health Nursing-Pediatrics
CiteScore
2.20
自引率
0.00%
发文量
105
审稿时长
12 weeks
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