一只患有抗利尿激素分泌不当特发性综合征的吉娃娃的长期治疗结果

IF 1.5 4区 农林科学 Q2 VETERINARY SCIENCES Journal of the American Animal Hospital Association Pub Date : 2024-11-01 DOI:10.5326/JAAHA-MS-7453
Darcy B Adin, Ilana Levinzon, Autumn N Harris
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引用次数: 0

摘要

一只约 3 岁大的雌性吉娃娃犬在被主人收养后出现多尿和多尿症状,前来接受评估。血清生化和尿液分析表明,该犬患低钠血症、低氯血症、低渗透压症,钠的部分排泄量正常。血清抗利尿激素浓度为 5.54 pg/mL,血清 copeptin 浓度为 135.40 pg/mL。抗利尿激素值高于健康犬的报告范围,根据血清渗透压,认为该值不合适。在排除使用利尿剂、肾脏疾病、肾上腺疾病和甲状腺功能障碍等其他潜在原因后,特发性抗利尿激素分泌不当综合征被认为是最有可能的诊断。确诊 2 年后,该犬临床状况良好,除饮食中补充少量食盐外,未接受其他特殊治疗。该病例之所以独特,是因为它没有全身或神经系统症状,无需治疗即可获得良好的长期疗效,而且使用了新型诊断测试。
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Long-term Outcome of a Chihuahua With Idiopathic Syndrome of Inappropriate Antidiuretic Hormone Secretion.

An approximately 3 yr old female Chihuahua was presented for evaluation of polyuria and polydipsia noted by the owner after adoption. Serum biochemistry and urinalysis revealed hyponatremia, hypochloremia, hypo-osmolality, and normal fractional excretion of sodium. Serum antidiuretic hormone concentration was 5.54 pg/mL and serum copeptin concentration was 135.40 pg/mL. The antidiuretic hormone value was above the reported range for healthy dogs and was considered inappropriate in light of serum osmolality. Idiopathic syndrome of inappropriate antidiuretic hormone secretion was considered the most likely diagnosis after excluding other potential causes, such as diuretic use, renal disease, adrenal disease, and thyroid dysfunction. The dog remains clinically well 2 yr after diagnosis without specific treatment other than minimal dietary salt supplementation. This case is unique because of the absence of systemic or neurologic signs, good long-term outcome without treatment, and use of novel diagnostic testing.

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来源期刊
CiteScore
2.70
自引率
0.00%
发文量
57
审稿时长
18-36 weeks
期刊介绍: The purpose of the JAAHA is to publish relevant, original, timely scientific and technical information pertaining to the practice of small animal medicine and surgery.
期刊最新文献
2022 AAHA Canine Vaccination Guidelines (2024 Update). 2024 AAHA Community Care Guidelines for Small Animal Practice. Long-term Outcome of a Chihuahua With Idiopathic Syndrome of Inappropriate Antidiuretic Hormone Secretion. Outcome, Complications, and Follow-Up in Dogs Treated with Pancarpal Arthrodesis Stabilized with Orthogonal Plates. Successful Management of Incompletely Resected Transitional Cell Carcinoma with Sorafenib Tosylate in a Dog.
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