与男性相比,因髋部骨折接受初级全髋关节置换术(THA)的女性住院死亡率较低

IF 2.2 3区 医学 Q3 CRITICAL CARE MEDICINE Injury-International Journal of the Care of the Injured Pub Date : 2024-10-19 DOI:10.1016/j.injury.2024.111970
Sumanth R. Chandrupatla , Jasvinder A. Singh
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引用次数: 0

摘要

导言我们评估了患者性别与美国髋部骨折初级全髋关节置换术(THA)后住院死亡率和出院处置的关系。方法利用 2016-2019 年美国全国住院患者样本 (NIS),我们计算了性别与髋部骨折原发性全髋关节置换术后并发症和住院死亡率的调整赔率比 (aOR) 和 95% 置信区间 (CI),并对人口统计学、健康的社会决定因素、医疗合并症、医院特征和术后并发症进行了调整。结果在 2016-2019 年 NIS 数据中,共有 400,930 例髋部骨折原发性全髋关节置换术住院患者。在多变量调整分析中,与男性相比,女性与髋部骨折 THA 术后较低的院内死亡率相关(aOR 0.65,95 % CI 0.58 - 0.74;p <0.001)。结论女性与髋部骨折 THA 术后较低的院内死亡率相关。要想在未来为男性取得更好的治疗效果,还需要进一步深入了解女性在接受髋部骨折 THA 术后死亡率降低的保护机制。
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Women undergoing primary total hip arthroplasty (THA) for hip fracture have lower in-hospital mortality compared to men

Introduction

We evaluated the association of patient sex with in-patient mortality and discharge disposition after primary total hip arthroplasty (THA) for hip fracture in the U.S.

Methods

Using the 2016–2019 U.S. National Inpatient Sample (NIS), we calculated adjusted odds ratios (aOR) and 95% confidence intervals (CI) of the association of sex with post-procedural complications and in-hospital mortality after primary THA for hip fracture, adjusting for demographics, social determinants of health, medical comorbidity, hospital characteristics, and post-procedural complications.

Results

There were 400,930 primary THA procedure hospitalizations for hip fracture in the 2016–2019 NIS data. In multivariable-adjusted analysis, compared to males, female sex was associated with lower in-hospital mortality following THA for hip fracture (aOR 0.65, 95 % CI 0.58 - 0.74; p < 0.001). Multivariable-adjusted analysis showed that female sex was associated with higher odds of discharge to a non-home destination after a THA for hip fracture (aOR 1.14, 95 % CI 1.07 - 1.22; p < 0.001).

Conclusions

Female sex was associated with lower in-hospital mortality after a THA for hip fracture. Further insights into the protective mechanisms that mediate this lower mortality in women undergoing a THA for hip fracture are needed to achieve better outcomes for men in the future.
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来源期刊
CiteScore
4.00
自引率
8.00%
发文量
699
审稿时长
96 days
期刊介绍: Injury was founded in 1969 and is an international journal dealing with all aspects of trauma care and accident surgery. Our primary aim is to facilitate the exchange of ideas, techniques and information among all members of the trauma team.
期刊最新文献
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