{"title":"从总肺活量推算被动呼气量可估测婴儿的呼气功能:一项回顾性研究","authors":"Avigdor Hevroni, Yael Simpson Lavy, Laurice Boursheh, Ephraim Bar-Yishay","doi":"10.1016/j.chest.2024.10.026","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Evaluating expiratory airway function in infants is challenging, as the gold standard, the raised-volume rapid thoraco-abdominal compression technique is technically difficult and has a high failure rate.</p><p><strong>Research question: </strong>Are measurements obtained during passive expiration from total lung capacity correlated with forced expiration measurements obtained by the raised-volume technique in infants?</p><p><strong>Study design and methods: </strong>This observational retrospective analysis included infants born ≥ 36 weeks gestation who underwent pulmonary function testing using the raised-volume rapid thoraco-abdominal compression technique at Hadassah Medical Centre between January 2011 and December 2019. Technically acceptable forced and passive flow-volume curve measurements were included in the analysis.</p><p><strong>Results: </strong>Out of 296 eligible infants, 276 (93%) had technically acceptable passive flow-volume curves while 226 (76%) had acceptable forced curves (p<0.001). The success rate of producing an acceptable curve was 70% for the passive curves and 39% for forced curves (p < 0.001). The Spearman correlation coefficients of vital capacity, expiratory volumes at 0.5 second, maximal expiratory flows, and expiratory flows at 50%, 75% and 85% of vital capacity were 0.92, 0.72, 0.83, 0.66, 0.67, 0.68, respectively (n= 226; p<0.001 for all). The correlation remained high regardless of the level of expiratory airway obstruction, gender or age. The mean inter-maneuver coefficients of variation were fairly low for both methods (5.2% vs 5.4%, p=NS).</p><p><strong>Interpretation: </strong>The passive flow-volume curve offers reliable and reproducible data with high correlation to the forced flow-volume curve. Therefore, the passive flow-volume curve can serve as an alternative tool in evaluating expiratory airway function in infants.</p>","PeriodicalId":9782,"journal":{"name":"Chest","volume":null,"pages":null},"PeriodicalIF":9.5000,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Passive Expiration from Total Lung Capacity Can Estimate Expiratory Function in Infants: A retrospective study.\",\"authors\":\"Avigdor Hevroni, Yael Simpson Lavy, Laurice Boursheh, Ephraim Bar-Yishay\",\"doi\":\"10.1016/j.chest.2024.10.026\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Evaluating expiratory airway function in infants is challenging, as the gold standard, the raised-volume rapid thoraco-abdominal compression technique is technically difficult and has a high failure rate.</p><p><strong>Research question: </strong>Are measurements obtained during passive expiration from total lung capacity correlated with forced expiration measurements obtained by the raised-volume technique in infants?</p><p><strong>Study design and methods: </strong>This observational retrospective analysis included infants born ≥ 36 weeks gestation who underwent pulmonary function testing using the raised-volume rapid thoraco-abdominal compression technique at Hadassah Medical Centre between January 2011 and December 2019. Technically acceptable forced and passive flow-volume curve measurements were included in the analysis.</p><p><strong>Results: </strong>Out of 296 eligible infants, 276 (93%) had technically acceptable passive flow-volume curves while 226 (76%) had acceptable forced curves (p<0.001). The success rate of producing an acceptable curve was 70% for the passive curves and 39% for forced curves (p < 0.001). The Spearman correlation coefficients of vital capacity, expiratory volumes at 0.5 second, maximal expiratory flows, and expiratory flows at 50%, 75% and 85% of vital capacity were 0.92, 0.72, 0.83, 0.66, 0.67, 0.68, respectively (n= 226; p<0.001 for all). The correlation remained high regardless of the level of expiratory airway obstruction, gender or age. The mean inter-maneuver coefficients of variation were fairly low for both methods (5.2% vs 5.4%, p=NS).</p><p><strong>Interpretation: </strong>The passive flow-volume curve offers reliable and reproducible data with high correlation to the forced flow-volume curve. Therefore, the passive flow-volume curve can serve as an alternative tool in evaluating expiratory airway function in infants.</p>\",\"PeriodicalId\":9782,\"journal\":{\"name\":\"Chest\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":9.5000,\"publicationDate\":\"2024-10-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chest\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.chest.2024.10.026\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chest","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.chest.2024.10.026","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
Passive Expiration from Total Lung Capacity Can Estimate Expiratory Function in Infants: A retrospective study.
Background: Evaluating expiratory airway function in infants is challenging, as the gold standard, the raised-volume rapid thoraco-abdominal compression technique is technically difficult and has a high failure rate.
Research question: Are measurements obtained during passive expiration from total lung capacity correlated with forced expiration measurements obtained by the raised-volume technique in infants?
Study design and methods: This observational retrospective analysis included infants born ≥ 36 weeks gestation who underwent pulmonary function testing using the raised-volume rapid thoraco-abdominal compression technique at Hadassah Medical Centre between January 2011 and December 2019. Technically acceptable forced and passive flow-volume curve measurements were included in the analysis.
Results: Out of 296 eligible infants, 276 (93%) had technically acceptable passive flow-volume curves while 226 (76%) had acceptable forced curves (p<0.001). The success rate of producing an acceptable curve was 70% for the passive curves and 39% for forced curves (p < 0.001). The Spearman correlation coefficients of vital capacity, expiratory volumes at 0.5 second, maximal expiratory flows, and expiratory flows at 50%, 75% and 85% of vital capacity were 0.92, 0.72, 0.83, 0.66, 0.67, 0.68, respectively (n= 226; p<0.001 for all). The correlation remained high regardless of the level of expiratory airway obstruction, gender or age. The mean inter-maneuver coefficients of variation were fairly low for both methods (5.2% vs 5.4%, p=NS).
Interpretation: The passive flow-volume curve offers reliable and reproducible data with high correlation to the forced flow-volume curve. Therefore, the passive flow-volume curve can serve as an alternative tool in evaluating expiratory airway function in infants.
期刊介绍:
At CHEST, our mission is to revolutionize patient care through the collaboration of multidisciplinary clinicians in the fields of pulmonary, critical care, and sleep medicine. We achieve this by publishing cutting-edge clinical research that addresses current challenges and brings forth future advancements. To enhance understanding in a rapidly evolving field, CHEST also features review articles, commentaries, and facilitates discussions on emerging controversies. We place great emphasis on scientific rigor, employing a rigorous peer review process, and ensuring all accepted content is published online within two weeks.