老年人因 COVID-19 住院而丧失的功能可通过住院康复恢复：系统回顾和荟萃分析。

IF 3.9 Experimental gerontology Pub Date : 2024-11-05 DOI:10.1016/j.exger.2024.112617

Henrique Monteiro Lapo , Amanda Veiga Sardeli , Lilian Oliveira Mariano , Fiona Jayne Howroyd , Paulo Roberto Sokoll , Elizabeth Sapey , Mara Patrícia Traina Chacon-Mikahil

{"title":"老年人因 COVID-19 住院而丧失的功能可通过住院康复恢复：系统回顾和荟萃分析。","authors":"Henrique Monteiro Lapo , Amanda Veiga Sardeli , Lilian Oliveira Mariano , Fiona Jayne Howroyd , Paulo Roberto Sokoll , Elizabeth Sapey , Mara Patrícia Traina Chacon-Mikahil","doi":"10.1016/j.exger.2024.112617","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Older adults are more likely to acquire the severe manifestation of COVID-19 and the hospitalised survivors experience significant functionality loss. Thus, we aimed to identify the level of functionality in older adults hospitalised due to COVID-19, and the effect of inpatient rehabilitation upon functional recovery.</div></div><div><h3>Methods</h3><div>A search was performed on July 2024, across five databases to retrieve studies assessing functionality in patients during COVID-19 hospitalisation, with or without rehabilitation.</div></div><div><h3>Results</h3><div>At admission, higher functionality was significantly higher for survivors than non survivors (standardized mean difference (SMD): 0.83 [0.56; 1.09]). The effect of inpatient rehabilitation on functionality was tested among 38 arms across studies. Inpatient rehabilitation improved functionality SMD across all indexes (1.47 [1.18; 1.77], <em>P</em> ≤ 0.001), with greatest effect in the patients >70 years (2.84 [1.74, 3.93], <em>P</em> = 0.006), compared to their counterparts.</div></div><div><h3>Conclusion</h3><div>Hospitalisation due to COVID-19 reduced functionality to a higher extent in older adults above 70 years. Inpatient rehabilitation was effective to improve functionality in both age groups.</div></div><div><h3>Protocol registration</h3><div>PROSPERO CRD42021278619.</div></div>","PeriodicalId":94003,"journal":{"name":"Experimental gerontology","volume":"198 ","pages":"Article 112617"},"PeriodicalIF":3.9000,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Functionality loss due to COVID-19 hospitalisation in older adults recovers with inpatient rehabilitation: A systematic review and meta-analysis\",\"authors\":\"Henrique Monteiro Lapo , Amanda Veiga Sardeli , Lilian Oliveira Mariano , Fiona Jayne Howroyd , Paulo Roberto Sokoll , Elizabeth Sapey , Mara Patrícia Traina Chacon-Mikahil\",\"doi\":\"10.1016/j.exger.2024.112617\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>Older adults are more likely to acquire the severe manifestation of COVID-19 and the hospitalised survivors experience significant functionality loss. Thus, we aimed to identify the level of functionality in older adults hospitalised due to COVID-19, and the effect of inpatient rehabilitation upon functional recovery.</div></div><div><h3>Methods</h3><div>A search was performed on July 2024, across five databases to retrieve studies assessing functionality in patients during COVID-19 hospitalisation, with or without rehabilitation.</div></div><div><h3>Results</h3><div>At admission, higher functionality was significantly higher for survivors than non survivors (standardized mean difference (SMD): 0.83 [0.56; 1.09]). The effect of inpatient rehabilitation on functionality was tested among 38 arms across studies. Inpatient rehabilitation improved functionality SMD across all indexes (1.47 [1.18; 1.77], <em>P</em> ≤ 0.001), with greatest effect in the patients >70 years (2.84 [1.74, 3.93], <em>P</em> = 0.006), compared to their counterparts.</div></div><div><h3>Conclusion</h3><div>Hospitalisation due to COVID-19 reduced functionality to a higher extent in older adults above 70 years. Inpatient rehabilitation was effective to improve functionality in both age groups.</div></div><div><h3>Protocol registration</h3><div>PROSPERO CRD42021278619.</div></div>\",\"PeriodicalId\":94003,\"journal\":{\"name\":\"Experimental gerontology\",\"volume\":\"198 \",\"pages\":\"Article 112617\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2024-11-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Experimental gerontology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0531556524002638\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental gerontology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0531556524002638","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

简介老年人更容易患上表现严重的 COVID-19，而住院幸存者的功能会明显减退。因此，我们旨在确定因 COVID-19 而住院的老年人的功能水平，以及住院康复对功能恢复的影响：方法：我们于 2024 年 7 月在五个数据库中进行了检索，以检索评估 COVID-19 住院期间患者功能的研究，无论是否进行了康复治疗：入院时，幸存者的功能显著高于非幸存者（标准化平均差异（SMD）：0.83 [0.56; 1.09]）。住院康复治疗对功能的影响在38项研究中进行了测试。与同类患者相比，住院康复治疗改善了所有指标的功能性SMD（1.47 [1.18; 1.77]，P ≤ 0.001），对70岁以上患者的影响最大（2.84 [1.74, 3.93]，P = 0.006）：结论：COVID-19导致的住院治疗对70岁以上老年人的功能影响更大。住院康复治疗可有效改善这两个年龄组的功能：PREMCORD42021278619。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

摘要图片

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Functionality loss due to COVID-19 hospitalisation in older adults recovers with inpatient rehabilitation: A systematic review and meta-analysis

Introduction

Older adults are more likely to acquire the severe manifestation of COVID-19 and the hospitalised survivors experience significant functionality loss. Thus, we aimed to identify the level of functionality in older adults hospitalised due to COVID-19, and the effect of inpatient rehabilitation upon functional recovery.

Methods

A search was performed on July 2024, across five databases to retrieve studies assessing functionality in patients during COVID-19 hospitalisation, with or without rehabilitation.

Results

At admission, higher functionality was significantly higher for survivors than non survivors (standardized mean difference (SMD): 0.83 [0.56; 1.09]). The effect of inpatient rehabilitation on functionality was tested among 38 arms across studies. Inpatient rehabilitation improved functionality SMD across all indexes (1.47 [1.18; 1.77], P ≤ 0.001), with greatest effect in the patients >70 years (2.84 [1.74, 3.93], P = 0.006), compared to their counterparts.

Conclusion

Hospitalisation due to COVID-19 reduced functionality to a higher extent in older adults above 70 years. Inpatient rehabilitation was effective to improve functionality in both age groups.