鹅掌楸科植物Bulbine inflata的定性和定量植物化学筛选及抗氧化潜力。

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY Pakistan journal of pharmaceutical sciences Pub Date : 2024-09-01
Rebecca Opeyemi Oyerinde, Ida Masana Risenga
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引用次数: 0

摘要

Bulbine inflata 是 Bulbine 属中尚未被记录有潜在药用价值的物种之一。因此,我们对其进行了初步的植物化学分析,并研究了其抗氧化潜力。我们采用风干和冷冻干燥技术将叶片干燥,并用水、甲醇、乙酸乙酯和正己烷进行提取。使用各种常见的颜色测试来检测植物化学物质的存在。其中一些植物化学物质被进一步量化。磷钼酸盐、2, 2 diphenyl-1-picryhydrazyl 、过氧化氢和金属螯合试验被用来评估 B. inflata 的抗氧化潜力。在 B. inflata 的叶片中检测到了单宁、类黄酮、酚类、苷类、甾体、香豆素、醌类、皂苷和萜类等植物化学物质。水提取物的总酚、类黄酮和单宁含量以及总抗氧化能力最高。B. inflata 对 DPPH、H2O2 和金属螯合具有中等到较高的抗氧化活性。在大多数检测中,冻干样品的结果都高于风干样品。研究结果表明,B. inflata 具有潜在的药用价值,可以在其盛行的社区内外扩大其民族药用资源。
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Qualitative and quantitative phytochemical screening and antioxidant potential of Bulbine inflata (Asphodelaceae).

Bulbine inflata is one of the species in the genus Bulbine that are yet to be documented for potential medicinal uses. Hence, we carried out its preliminary phytochemical profiling and investigated its antioxidant potential. The leaves were dried using air- and freeze-drying techniques and were extracted by water, methanol, ethyl acetate and hexane. Various common colour tests were used for the presence of phytochemicals. Some of the phytochemicals were further quantified. Phosphomolybdate, 2, 2 diphenyl-1-picryhydrazyl, hydrogen peroxide and metal chelating assays were used to assess the antioxidant potential of B. inflata. Tannin, flavonoids, phenols, glycosides, steroids, coumarins, quinones, saponins and terpenoids were detected phytochemicals in B. inflata leaves. The highest total phenolic, flavonoid and tannin contents, as well as total antioxidant capacity, were recorded for water extract. B. inflata showed moderate to high antioxidant activities against DPPH, H2O2 and metal chelating. Freeze-dried samples presented with higher results than air-dried samples in most assays. The results showed the potential of B. inflata for medicinal uses and could expand the ethnomedicinal resources in the communities where it is prevalent and beyond.

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来源期刊
CiteScore
1.40
自引率
12.50%
发文量
211
审稿时长
4.5 months
期刊介绍: Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.
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