{"title":"拟南芥 E3 泛素连接酶 DOA10A 在 ABA 信号转导过程中通过单泛素化促进脱落酸（ABA）受体定位到膜上。","authors":"Cuixia Liu, Qingliang Li, Zhengwei Shen, Ran Xia, Qian Chen, Xiao Li, Yanglin Ding, Shuhua Yang, Giovanna Serino, Qi Xie, Feifei Yu","doi":"10.1111/nph.20224","DOIUrl":null,"url":null,"abstract":"<p>\n </p>","PeriodicalId":214,"journal":{"name":"New Phytologist","volume":"245 1","pages":"169-182"},"PeriodicalIF":8.7000,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/nph.20224","citationCount":"0","resultStr":"{\"title\":\"The Arabidopsis E3 ubiquitin ligase DOA10A promotes localization of abscisic acid (ABA) receptors to the membrane through mono-ubiquitination in ABA signaling\",\"authors\":\"Cuixia Liu, Qingliang Li, Zhengwei Shen, Ran Xia, Qian Chen, Xiao Li, Yanglin Ding, Shuhua Yang, Giovanna Serino, Qi Xie, Feifei Yu\",\"doi\":\"10.1111/nph.20224\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>\\n </p>\",\"PeriodicalId\":214,\"journal\":{\"name\":\"New Phytologist\",\"volume\":\"245 1\",\"pages\":\"169-182\"},\"PeriodicalIF\":8.7000,\"publicationDate\":\"2024-12-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/nph.20224\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"New Phytologist\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/nph.20224\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/11/4 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"PLANT SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"New Phytologist","FirstCategoryId":"99","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/nph.20224","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/4 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 0
摘要
内质网相关降解（ERAD）系统能消除折叠错误和寿命短的蛋白质，以维持细胞的生理平衡。我们以前曾报道过，ERAD 参与了拟南芥的耐盐性。鉴于植物激素脱落酸（ABA）在植物胁迫响应中的核心作用，我们试图找出 ABA 和 ERAD 途径在植物胁迫响应中的潜在交叉点。通过筛选一系列ERAD突变体的ABA反应，我们分离出了一个功能增益突变体doa10a-1，它能使幼苗对ABA过敏。遗传和生化分析表明，DOA10A 是一种功能性 E3 泛素连接酶，它与特定的 E2 酶协同作用，介导 ABA 受体的单泛素化，然后将其重新定位到质膜上。这反过来又会增强对 ABA 的感知。总之，我们在此报告发现了一种新型 RING 型 E3 连接酶 DOA10A，它通过单泛素化影响 ABA 受体的定位和活性来调节 ABA 感知。
The Arabidopsis E3 ubiquitin ligase DOA10A promotes localization of abscisic acid (ABA) receptors to the membrane through mono-ubiquitination in ABA signaling
期刊介绍：
New Phytologist is an international electronic journal published 24 times a year. It is owned by the New Phytologist Foundation, a non-profit-making charitable organization dedicated to promoting plant science. The journal publishes excellent, novel, rigorous, and timely research and scholarship in plant science and its applications. The articles cover topics in five sections: Physiology & Development, Environment, Interaction, Evolution, and Transformative Plant Biotechnology. These sections encompass intracellular processes, global environmental change, and encourage cross-disciplinary approaches. The journal recognizes the use of techniques from molecular and cell biology, functional genomics, modeling, and system-based approaches in plant science. Abstracting and Indexing Information for New Phytologist includes Academic Search, AgBiotech News & Information, Agroforestry Abstracts, Biochemistry & Biophysics Citation Index, Botanical Pesticides, CAB Abstracts®, Environment Index, Global Health, and Plant Breeding Abstracts, and others.
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