Lin-Lin Ma, Ke-Xin Xu, Bao-Lin Xiao, Sanad Abdalbage Mohammed Abdalsadeg, Yu-Jie Chen, Yu-Ying Li, Jun Hong, Ali Akbar Moosavi-Movahedi
{"title":"一种基于 NH2-MWCNTS-CMC 和 ZIF-67 过氧化物酶样纳米复合材料的电化学传感器,用于灵敏检测木犀草素","authors":"Lin-Lin Ma, Ke-Xin Xu, Bao-Lin Xiao, Sanad Abdalbage Mohammed Abdalsadeg, Yu-Jie Chen, Yu-Ying Li, Jun Hong, Ali Akbar Moosavi-Movahedi","doi":"10.1007/s13738-024-03122-7","DOIUrl":null,"url":null,"abstract":"<div><p>Luteolin (Lut) is a flavonoid compound with antioxidant, anti-inflammatory and other biological properties. Lut has been used in many fields such as biomedicine and food safety. Therefore, the quantitative measurement of Lut is of great significance. In this study, an electrochemical sensor based on aminated multi-walled carbon (NH<sub>2</sub>-MWCNTs), sodium carboxymethylcellulose (CMC), ZIF-67 and chitosan (Chi) is developed for the measurement of Lut. NH<sub>2</sub>-MWCNTs are better dispersed by CMC, and NH<sub>2</sub>-MWCNTs are cross-linked with ZIF-67, which further improves the response and sensitivity of the electrode to the Lut due to the peroxide-like properties of ZIF-67. The detection limit and linear range of the electrochemical sensor for Lut are 2.1 nM and 0.1–7 μM, respectively. Dandelion is a traditional Chinese medicine plant containing Lut component. The prepared electrochemical sensor is also used to analysis Lut content in various parts of dandelion. The results show that the flowers part of dandelion exhibits the highest concentration of Lut; while, the leaves contain a moderate amount, and the roots are nearly devoid of Lut. These results are consistent with those obtained by ultra-high performance liquid chromatography. The electrochemical sensor has good stability and anti-interference ability, and has good potential application value in drug concentration detection and screening.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":676,"journal":{"name":"Journal of the Iranian Chemical Society","volume":null,"pages":null},"PeriodicalIF":2.2000,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An electrochemical sensor based on NH2-MWCNTS-CMC and ZIF-67 peroxidase-like nanocomposite for sensitive luteolin detection\",\"authors\":\"Lin-Lin Ma, Ke-Xin Xu, Bao-Lin Xiao, Sanad Abdalbage Mohammed Abdalsadeg, Yu-Jie Chen, Yu-Ying Li, Jun Hong, Ali Akbar Moosavi-Movahedi\",\"doi\":\"10.1007/s13738-024-03122-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Luteolin (Lut) is a flavonoid compound with antioxidant, anti-inflammatory and other biological properties. Lut has been used in many fields such as biomedicine and food safety. Therefore, the quantitative measurement of Lut is of great significance. In this study, an electrochemical sensor based on aminated multi-walled carbon (NH<sub>2</sub>-MWCNTs), sodium carboxymethylcellulose (CMC), ZIF-67 and chitosan (Chi) is developed for the measurement of Lut. NH<sub>2</sub>-MWCNTs are better dispersed by CMC, and NH<sub>2</sub>-MWCNTs are cross-linked with ZIF-67, which further improves the response and sensitivity of the electrode to the Lut due to the peroxide-like properties of ZIF-67. The detection limit and linear range of the electrochemical sensor for Lut are 2.1 nM and 0.1–7 μM, respectively. Dandelion is a traditional Chinese medicine plant containing Lut component. The prepared electrochemical sensor is also used to analysis Lut content in various parts of dandelion. The results show that the flowers part of dandelion exhibits the highest concentration of Lut; while, the leaves contain a moderate amount, and the roots are nearly devoid of Lut. These results are consistent with those obtained by ultra-high performance liquid chromatography. The electrochemical sensor has good stability and anti-interference ability, and has good potential application value in drug concentration detection and screening.</p><h3>Graphical Abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":676,\"journal\":{\"name\":\"Journal of the Iranian Chemical Society\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2024-10-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Iranian Chemical Society\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s13738-024-03122-7\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Iranian Chemical Society","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s13738-024-03122-7","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
An electrochemical sensor based on NH2-MWCNTS-CMC and ZIF-67 peroxidase-like nanocomposite for sensitive luteolin detection
Luteolin (Lut) is a flavonoid compound with antioxidant, anti-inflammatory and other biological properties. Lut has been used in many fields such as biomedicine and food safety. Therefore, the quantitative measurement of Lut is of great significance. In this study, an electrochemical sensor based on aminated multi-walled carbon (NH2-MWCNTs), sodium carboxymethylcellulose (CMC), ZIF-67 and chitosan (Chi) is developed for the measurement of Lut. NH2-MWCNTs are better dispersed by CMC, and NH2-MWCNTs are cross-linked with ZIF-67, which further improves the response and sensitivity of the electrode to the Lut due to the peroxide-like properties of ZIF-67. The detection limit and linear range of the electrochemical sensor for Lut are 2.1 nM and 0.1–7 μM, respectively. Dandelion is a traditional Chinese medicine plant containing Lut component. The prepared electrochemical sensor is also used to analysis Lut content in various parts of dandelion. The results show that the flowers part of dandelion exhibits the highest concentration of Lut; while, the leaves contain a moderate amount, and the roots are nearly devoid of Lut. These results are consistent with those obtained by ultra-high performance liquid chromatography. The electrochemical sensor has good stability and anti-interference ability, and has good potential application value in drug concentration detection and screening.
期刊介绍:
JICS is an international journal covering general fields of chemistry. JICS welcomes high quality original papers in English dealing with experimental, theoretical and applied research related to all branches of chemistry. These include the fields of analytical, inorganic, organic and physical chemistry as well as the chemical biology area. Review articles discussing specific areas of chemistry of current chemical or biological importance are also published. JICS ensures visibility of your research results to a worldwide audience in science. You are kindly invited to submit your manuscript to the Editor-in-Chief or Regional Editor. All contributions in the form of original papers or short communications will be peer reviewed and published free of charge after acceptance.