乳糜泻对生育和怀孕的影响:一项意大利调查。

IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Archives of Gynecology and Obstetrics Pub Date : 2024-11-05 DOI:10.1007/s00404-024-07781-y
Martina Arcieri, Carlotta Abrami, Annalisa Graziano, Stefano Restaino, Elisa Barbui, Elisa Rizzante, Silvia D'Ippolito, Giuseppe Vizzielli, Lorenza Driul
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引用次数: 0

摘要

背景:乳糜泻(CD)是一种炎症性肠病,与妇产科疾病有关。然而,由于人们误认为乳糜泻仅仅是一种胃肠道疾病,妇科医生仍未对其进行充分检测。目的:本研究旨在评估乳糜泻与妇产科并发症之间的关联,强调告知患者乳糜泻表现的重要性,并评估患者对医护人员提供的疾病信息的满意度:方法:通过意大利乳糜泻协会网站对乳糜泻妇女进行数字调查:我们对 493 份问卷进行了分析。11.7%的受访者因产科和妇科疾病而被诊断为乳糜泻。研究显示,未经治疗的 CD 患者更容易流产(诊断前/后分别为 41.8% vs 34%,P = 0.111)、妊娠贫血(诊断前/后分别为 71.4% vs 40.4%,P 结论:我们的研究有助于加深对 CD 患者的了解:我们的研究有助于更深入地了解 CD 与生殖结果之间的关系,突出了与之相关的主要妇产科问题。它强调了患者视角的重要性以及医护人员提高对乳糜泻认识的必要性。
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The influence of celiac disease on fertility and pregnancy: an Italian survey.

Background: Celiac disease (CD) is an inflammatory enteropathy that has been associated to obstetric and gynecological disorders. However, it is still not adequately tested by gynecologists due to the misconception that it is solely a gastrointestinal disease. This underestimation requires the development of targeted interventions.

Purpose: This study aims to evaluate the association between CD and obstetric/gynecological complications, highlight the importance of informing patients about CD manifestations, and assess the patient satisfaction with the information provided by healthcare professionals on the disease.

Methods: A digital survey was administered to celiac women via the Italian Celiac Association's website.

Results: We analyzed 493 questionnaires. Obstetric and gynecological disorders led to the diagnosis of CD in 11.7% of interviewed. The study revealed that untreated CD patients are more predisposed to miscarriages (41.8% vs 34% before/after diagnosis, respectively, p = 0.111), anemia in pregnancy (71.4% vs 40.4% before/after diagnosis, respectively, p < 0.001) and the risk of low birth weight (newborns weighing < 1500 g were 4.0% before and 1.1% after the gluten-free diet, p = 0.028). Women with CD, both before and after gluten-free diet, had higher infertility rates (about 19%) than the general population. Additionally, 73% of interviewees were dissatisfied with the information they received from health professionals about the reproductive implications of CD.

Conclusion: Our research contributes to a deeper understanding of the intersection between CD and reproductive outcomes, highlighting the main obstetric and gynecological problems related to it. It emphasizes the importance of patient's perspective and the need for greater awareness about celiac disease from healthcare workers.

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来源期刊
CiteScore
4.70
自引率
15.40%
发文量
493
审稿时长
1 months
期刊介绍: Founded in 1870 as "Archiv für Gynaekologie", Archives of Gynecology and Obstetrics has a long and outstanding tradition. Since 1922 the journal has been the Organ of the Deutsche Gesellschaft für Gynäkologie und Geburtshilfe. "The Archives of Gynecology and Obstetrics" is circulated in over 40 countries world wide and is indexed in "PubMed/Medline" and "Science Citation Index Expanded/Journal Citation Report". The journal publishes invited and submitted reviews; peer-reviewed original articles about clinical topics and basic research as well as news and views and guidelines and position statements from all sub-specialties in gynecology and obstetrics.
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