表面增强拉曼光谱在天然产品研究中的综合应用与前景。

IF 4.2 2区 化学 Q1 CHEMISTRY, ANALYTICAL Critical reviews in analytical chemistry Pub Date : 2024-11-06 DOI:10.1080/10408347.2024.2424232
Ling Xia, Huimin Yu, Yang Li
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引用次数: 0

摘要

天然产品的成分多样而复杂,因此准确分析是一项具有挑战性的任务。表面增强拉曼光谱(SERS)为天然产品的分析提供了一种方法。这篇综述深入探讨了 SERS 在天然产品领域的应用,从成分鉴定和质量控制到阐明作用机制。它强调了 SERS 识别复杂混合物中活性成分和监控生产以保证质量的能力。SERS 还能阐明作用机制。然而,底物标准化和数据处理的复杂性等挑战依然存在。未来的发展将侧重于创新设计、自动化和集成。通过不断创新和跨学科合作,SERS有望在天然产物的研究和开发中发挥重要作用,进一步促进天然产物产业的发展。本综述旨在为天然产品的质量控制和新药开发提供全面的视角和支持。
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Comprehensive Application and Prospects of Surface-Enhanced Raman Spectroscopy in Natural Product Research.

The compositions of natural products are diverse and complex, which makes accurate analysis a challenging task. Surface-enhanced Raman spectroscopy (SERS) provides a means for the analysis of natural products. This review thoroughly examines the applications of SERS in the field of natural products, ranging from component identification and quality control to the clarification of mechanisms of action. It emphasizes SERS' capability to identify active ingredients in complex mixtures and monitor production for quality assurance. SERS can also elucidate the mechanisms of action. Nevertheless, challenges such as substrate standardization and the complexity of data processing exist. Future development will focus on innovative design, automation, and integration. Through continuous innovation and interdisciplinary collaboration, SERS is expected to play a crucial role in natural product research and development, further promoting the growth of the natural product industry. This review aims to provide a comprehensive perspective and support for natural product quality control and new drug development.

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来源期刊
CiteScore
12.00
自引率
4.00%
发文量
137
审稿时长
6 months
期刊介绍: Critical Reviews in Analytical Chemistry continues to be a dependable resource for both the expert and the student by providing in-depth, scholarly, insightful reviews of important topics within the discipline of analytical chemistry and related measurement sciences. The journal exclusively publishes review articles that illuminate the underlying science, that evaluate the field''s status by putting recent developments into proper perspective and context, and that speculate on possible future developments. A limited number of articles are of a "tutorial" format written by experts for scientists seeking introduction or clarification in a new area. This journal serves as a forum for linking various underlying components in broad and interdisciplinary means, while maintaining balance between applied and fundamental research. Topics we are interested in receiving reviews on are the following: · chemical analysis; · instrumentation; · chemometrics; · analytical biochemistry; · medicinal analysis; · forensics; · environmental sciences; · applied physics; · and material science.
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