HLA 系统因子命名法,2024 年 7 月、8 月和 9 月更新。

IF 5.9 4区 医学 Q2 CELL BIOLOGY HLA Pub Date : 2024-11-05 DOI:10.1111/tan.15732
Steven G. E. Marsh, WHO Nomenclature Committee for Factors of the HLA System
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引用次数: 0

摘要

自 2024 年 4 月、5 月和 6 月的命名更新[1]以来,以下序列已提交命名委员会,并已按照商定的政策被指定为正式等位基因[2]。下面列出了新分配的序列(表 1)和先前报告序列的确认(表 2)。下面列出了新分配的序列(表 1)和以前报告的确认序列(表 2),并给出了每个序列的登录号,这些登录号可用于从 EMBL、GenBank 或 DDBJ 数据库中检索序列文件。虽然数据图书馆已经分配了登录号,而且大多数序列都已经可用,但仍有可能存在作者尚未允许发布序列的情况;在这种情况下,您必须直接联系提交序列的作者。与新序列有关的其他信息通常包含在描述这些等位基因的出版物中;表 3 列出了最近发表的描述新 HLA 序列的出版物。现在,所有新序列和确证序列都应使用提供的序列提交工具[5, 6],通过 IPD-IMGT/HLA 数据库直接提交给世界卫生组织 HLA 系统因子命名委员会。IPD-IMGT/HLA 数据库可通过万维网访问: www.ebi.ac.uk/ipd/imgt/hla.The 作者声明无利益冲突。
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Nomenclature for Factors of the HLA System, Update July, August and September 2024

The following sequences have been submitted to the Nomenclature Committee since the April, May and June 2024 nomenclature update [1] and, following agreed policy, have been assigned official allele designations [2]. Full details of all sequences will be published in a forthcoming report.

Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3. An additional 221 alleles were recently published but have not been included in Table 3 due to space considerations [3, 4].

All new and confirmatory sequences should now be submitted directly to the WHO Nomenclature Committee for Factors of the HLA System via the IPD-IMGT/HLA Database using the sequence submission tool provided [5, 6]. The IPD-IMGT/HLA Database may be accessed via the World Wide Web at: www.ebi.ac.uk/ipd/imgt/hla.

The authors declare no conflicts of interest.

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来源期刊
HLA
HLA Immunology and Microbiology-Immunology
CiteScore
3.00
自引率
28.80%
发文量
368
期刊介绍: HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.
期刊最新文献
The Full-Length Genomic Sequence of the HLA-B*46:01:25 Allele The HLA-A Allele, HLA-A*11:01:01:07, Identified by Third-Generation Sequencing The HLA-B*27:264 Allele Identified in a Volunteer Donor for Haematopoietic Stem Cell Transplant Characterisation of the Novel HLA-A*23:147 Allele Using New Next-Generation Sequencing Methods Identification of the Novel HLA-DPA1*01:214 Allele in a Brazilian Bone Marrow Donor
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