通过日粮苏氨酸水平和油脂添加优化肉鸡的生长、免疫力和基因表达。

IF 1.8 3区 农林科学 Q2 VETERINARY SCIENCES Veterinary Medicine and Science Pub Date : 2024-11-01 DOI:10.1002/vms3.70046
Mohamed I El-Katcha, Mosaad A Soltan, Heba I Ghamry, Abeer F El-Nahas, Laila A Al-Shuraym, Ostan Mihaela, Rada Olga, Rasha E Azab, Ahmed Abdeen, Mustafa Shukry, Set A El-Shobokshy
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引用次数: 0

摘要

背景:在家禽营养中添加合成氨基酸对促进免疫球蛋白的合成和提高氨基酸谱的整体全面性具有重要作用:本研究探讨了摄入不同含量的苏氨酸(Thr)和低油或高油对肉鸡生长和免疫力的影响:我们研究了肉鸡的生长性能、饲料效率、免疫反应、肠道形态、吸收能力,以及与采食量(前表皮促皮质素[POMC])、脂肪酸合成(乙酰-CoA 羧化酶[ACC])、免疫(脂多糖诱导的肿瘤坏死样α因子[LITAF])和热休克蛋白 70(HSP70)相关的一些基因的表达。使用了 8 组小鸡,包括 4 种日粮 Thr 水平(100%、115%、130% 或 145%)和两种油水平(葵花籽油 50% 和大豆油 50% 的混合物):(对照组)和高日粮:较高的日粮Thr水平(145%)和高含油量显著增加了ACC和POMC基因的表达,导致采食量、体重增加(BWG)和肝脏脂肪含量最低。对于肉鸡来说,高油和 115% Thr 的组合是最佳的。这些肉鸡的生长性能、免疫参数和肠道健康状况均有显著提高(p ≤ .05),ACC、POMC、HSP70和LITAF的表达量也最低,这反映在较高的饲料转化率和较低的脂肪肝发病率、抗热性和免疫状态上:高油和 115% Thr 水平的组合优化了肉鸡的健康和生产率,提高了生长、免疫功能和肠道健康。这种日粮降低了与脂肪肝和应激有关的基因表达,从而提高了饲料效率、耐热性和整体健康水平。采用这些日粮调整可以提高家禽养殖业的基本生产指标,从而改善肉鸡的生产性能和经济可行性。
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Optimising Growth, Immunity, and Gene Expression in Broiler Chickens Through Dietary Threonine Levels and Oil Inclusion.

Background: The inclusion of synthetic amino acids in poultry nutrition plays a crucial role in both enhancing the synthesis of immunoglobulins and elevating the overall comprehensiveness of the amino acid profile.

Objectives: This research examined the effects of consuming threonine (Thr) in various forms levels with low or high oil on broiler chickens' growth and immunity.

Methods: We investigate the growth performance, feed efficiency, immune response, intestinal morphology, absorptive capacity, and expression of some genes related to the feed intake (Pro-opiomelanocortin [POMC]), fatty acid synthesis (Acetyl-CoA Carboxylase [ACC]), immunity (lipopolysaccharide-induced tumour necrosis like alpha factor [LITAF]), and heat shock protein 70 (HSP70). Eight groups of chicks were used, including four dietary Thr levels (100%, 115%, 130%, or 145%) with two oil levels (mixture of sunflower 50% and soybean oils 50%): (control) and high.

Results: The higher dietary Thr level (145%) with high oil inclusion significantly increased ACC and POMC gene expression, resulting in the lowest feed intake, body weight gain (BWG), and liver fat content. Combining high oil with 115% Thr was the optimum for the broilers. The birds have significant (p ≤ .05) growth performance, immune parameters, and intestinal health, as well as the lowest expression of ACC, POMC, HSP70, and LITAF, which was reflected in better feed conversion ratio and lower incidence of fatty liver, thermo-resistance, and immune status of the birds.

Conclusions: The combination of high oil and 115% Thr levels optimises broiler health and productivity, enhancing growth, immune function, and gut health. This diet lowers the expression of genes associated with fatty liver and stress, leading to better feed efficiency, thermo-resistance, and overall well-being. Adopting these dietary adjustments can improve broiler performance and economic viability in poultry farming by enhancing essential productivity metrics.

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来源期刊
Veterinary Medicine and Science
Veterinary Medicine and Science Veterinary-General Veterinary
CiteScore
3.00
自引率
0.00%
发文量
296
期刊介绍: Veterinary Medicine and Science is the peer-reviewed journal for rapid dissemination of research in all areas of veterinary medicine and science. The journal aims to serve the research community by providing a vehicle for authors wishing to publish interesting and high quality work in both fundamental and clinical veterinary medicine and science. Veterinary Medicine and Science publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper. We aim to be a truly global forum for high-quality research in veterinary medicine and science, and believe that the best research should be published and made widely accessible as quickly as possible. Veterinary Medicine and Science publishes papers submitted directly to the journal and those referred from a select group of prestigious journals published by Wiley-Blackwell. Veterinary Medicine and Science is a Wiley Open Access journal, one of a new series of peer-reviewed titles publishing quality research with speed and efficiency. For further information visit the Wiley Open Access website.
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