Xinfeng Zhang , Nazeer Muhammad Nouman , Caixia Yin , Fangjun Huo
{"title":"有机小分子荧光探针在缺血再灌注损伤中的应用综述","authors":"Xinfeng Zhang , Nazeer Muhammad Nouman , Caixia Yin , Fangjun Huo","doi":"10.1016/j.dyepig.2024.112524","DOIUrl":null,"url":null,"abstract":"<div><div>Ischemia-reperfusion injury is closely linked to oxidative stress, which arises from the complicated metabolism of substances and energy. There is a growing inclination towards developing and applying fluorescent probe tools to explore this phenomenon's physiological and pathological mechanisms. Starting from the pathophysiology of ischemia-reperfusion injury in various organs, this review will provide a comprehensive overview of the research advancements related to developing and applying fluorescence probes for studying ischemia-reperfusion diseases. We will examine the use of small molecule fluorescence probes in the context of ischemia-reperfusion in various tissues and organs. Our focus will include liver, brain, kidney, and myocardial ischemia-reperfusion and other related conditions. In addition, this comment will deeply reflect on and analyze the development direction of fluorescent probes for ischemia-reperfusion injury, highlighting their potential for accurate clinical diagnosis and application research. This discussion aims to inspire hope and optimism in the audience about the future of medical research.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"233 ","pages":"Article 112524"},"PeriodicalIF":4.1000,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A review of the application of small organic molecule fluorescent probes in ischemia-reperfusion injury\",\"authors\":\"Xinfeng Zhang , Nazeer Muhammad Nouman , Caixia Yin , Fangjun Huo\",\"doi\":\"10.1016/j.dyepig.2024.112524\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Ischemia-reperfusion injury is closely linked to oxidative stress, which arises from the complicated metabolism of substances and energy. There is a growing inclination towards developing and applying fluorescent probe tools to explore this phenomenon's physiological and pathological mechanisms. Starting from the pathophysiology of ischemia-reperfusion injury in various organs, this review will provide a comprehensive overview of the research advancements related to developing and applying fluorescence probes for studying ischemia-reperfusion diseases. We will examine the use of small molecule fluorescence probes in the context of ischemia-reperfusion in various tissues and organs. Our focus will include liver, brain, kidney, and myocardial ischemia-reperfusion and other related conditions. In addition, this comment will deeply reflect on and analyze the development direction of fluorescent probes for ischemia-reperfusion injury, highlighting their potential for accurate clinical diagnosis and application research. This discussion aims to inspire hope and optimism in the audience about the future of medical research.</div></div>\",\"PeriodicalId\":302,\"journal\":{\"name\":\"Dyes and Pigments\",\"volume\":\"233 \",\"pages\":\"Article 112524\"},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2024-10-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dyes and Pigments\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0143720824005904\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dyes and Pigments","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0143720824005904","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
A review of the application of small organic molecule fluorescent probes in ischemia-reperfusion injury
Ischemia-reperfusion injury is closely linked to oxidative stress, which arises from the complicated metabolism of substances and energy. There is a growing inclination towards developing and applying fluorescent probe tools to explore this phenomenon's physiological and pathological mechanisms. Starting from the pathophysiology of ischemia-reperfusion injury in various organs, this review will provide a comprehensive overview of the research advancements related to developing and applying fluorescence probes for studying ischemia-reperfusion diseases. We will examine the use of small molecule fluorescence probes in the context of ischemia-reperfusion in various tissues and organs. Our focus will include liver, brain, kidney, and myocardial ischemia-reperfusion and other related conditions. In addition, this comment will deeply reflect on and analyze the development direction of fluorescent probes for ischemia-reperfusion injury, highlighting their potential for accurate clinical diagnosis and application research. This discussion aims to inspire hope and optimism in the audience about the future of medical research.
期刊介绍：
Dyes and Pigments covers the scientific and technical aspects of the chemistry and physics of dyes, pigments and their intermediates. Emphasis is placed on the properties of the colouring matters themselves rather than on their applications or the system in which they may be applied.
Thus the journal accepts research and review papers on the synthesis of dyes, pigments and intermediates, their physical or chemical properties, e.g. spectroscopic, surface, solution or solid state characteristics, the physical aspects of their preparation, e.g. precipitation, nucleation and growth, crystal formation, liquid crystalline characteristics, their photochemical, ecological or biological properties and the relationship between colour and chemical constitution. However, papers are considered which deal with the more fundamental aspects of colourant application and of the interactions of colourants with substrates or media.
The journal will interest a wide variety of workers in a range of disciplines whose work involves dyes, pigments and their intermediates, and provides a platform for investigators with common interests but diverse fields of activity such as cosmetics, reprographics, dye and pigment synthesis, medical research, polymers, etc.
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