CT metal artefact reduction for hip and shoulder implants using novel algorithms and machine learning: A systematic review with pairwise and network meta-analyses

Introduction

Many tools have been developed to reduce metal artefacts in computed tomography (CT) images resulting from metallic prosthesis; however, their relative effectiveness in preserving image quality is poorly understood. This paper reviews the literature on novel metal artefact reduction (MAR) methods targeting large metal artefacts in fan-beam CT to examine their effectiveness in reducing metal artefacts and effect on image quality.

Methods

The PRISMA checklist was used to search for articles in five electronic databases (MEDLINE, Scopus, Web of Science, IEEE, EMBASE). Studies that assessed the effectiveness of recently developed MAR method on fan-beam CT images of hip and shoulder implants were reviewed. Study quality was assessed using the National Institute of Health (NIH) tool. Meta-analyses were conducted in R, and results that could not be meta-analysed were synthesised narratively.

Results

Thirty-six studies were reviewed. Of these, 20 studies proposed statistical algorithms and 16 used machine learning (ML), and there were 19 novel comparators. Network meta-analysis of 19 studies showed that Recurrent Neural Network MAR (RNN-MAR) is more effective in reducing noise (LogOR 20.7; 95 % CI 12.6–28.9) without compromising image quality (LogOR 4.4; 95 % CI -13.8-22.5). The network meta-analysis and narrative synthesis showed novel MAR methods reduce noise more effectively than baseline algorithms, with five out of 23 ML methods significantly more effective than Filtered Back Projection (FBP) (p < 0.05). Computation time varied, but ML methods were faster than statistical algorithms.

Conclusion

ML tools are more effective in reducing metal artefacts without compromising image quality and are computationally faster than statistical algorithms. Overall, novel MAR methods were also more effective in reducing noise than the baseline reconstructions.

Implications for practice

Implementation research is needed to establish the clinical suitability of ML MAR in practice.