Host-Parasite interaction between brown algae and eukaryote biotrophic pathogens

Brown algae belong to the class Phaeophyceae which are mainly multicellular, photosynthetic organisms, however they evolved independently from terrestrial plants, green and red algae. In the past years marine aquaculture involving brown algae has gained enormous momentum. In both natural environments and aquaculture, brown algae are susceptible to infection by various prokaryotic and eukaryotic parasites. While our understanding of host-parasite interactions in brown algae is gaining recognition, our understanding of how brown algae react to biotic stress remains incomplete. The objective of this review is to address research gaps in the field by providing a summary of what is already known about the response of brown algae to abiotic and biotic stress. The biology of eukaryotic zoosporic pathogens Maullinia ectocarpii, Eurychasma dicksonii, Anisolpidium ectocarpii is also discussed, as those parasites have been used in laboratory experiments to study diseases of brown algae. These studies often relied on parasites-infecting Ectocarpus siliculosus which has become a brown algal model organism to study host-pathogen interactions. Stress response in brown algae involves processes similar to hypersensitivity response, oxidative stress response, and activation of peroxidases, but also the production of blue fluorescent metabolites and deposition of β-1,3-glucan in the cell wall. Cell wall modification, expression of several defence related proteins, and secondary metabolite production also hold a crucial role in brown algal defence mechanism. Understanding host-pathogen interactions and the associated mechanisms is vital to discover strategies to control pathogens in the growing aquaculture sector.