南卡罗来纳州一家三级护理医院中耐受奥沙西林的金黄色葡萄球菌(BORSA)的低流行率

IF 1.8 Q3 INFECTIOUS DISEASES Infection Prevention in Practice Pub Date : 2024-10-28 DOI:10.1016/j.infpip.2024.100414
Connor Horne , Gabrielle DiMattia , Nicholas Perkins , Prerana Roth
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引用次数: 0

摘要

金黄色葡萄球菌血流感染的及时治疗通常取决于已知的诊断检测方法,以区分甲氧西林敏感金黄色葡萄球菌(MSSA)和耐甲氧西林金黄色葡萄球菌(MRSA)。耐边界奥沙西林金黄色葡萄球菌(BORSA)是一种罕见的、非mecA介导的表型,其耐药机制尚不清楚,但可能会产生重大影响,因为它经常被误认为是MSSA,但表现得更像MRSA。我们对 MSSA 血流感染进行了回顾性分析,以确定 BORSA 的流行率。我院发现 BORSA 感染率为 0.1%,与文献报道一致。虽然流行率较低,但由于机制不明确和检测方法不可靠,BORSA 可能会对治疗和流行病学构成威胁。
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Low prevalence of borderline oxacillin resistant Staphylococcus aureus (BORSA) in a tertiary care hospital in South Carolina
Prompt treatment for Staphylococcus aureus bloodstream infections is often dependent on known diagnostic testing modalities to differentiate between methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA). Borderline-oxacillin resistant S. aureus (BORSA), a rare, non-mecA mediated phenotype, has unclear resistance mechanisms but potentially significant consequences as it is frequently misidentified as MSSA but behaves more like MRSA. A retrospective analysis was performed of MSSA bloodstream infections to determine the prevalence of BORSA. Our institution found BORSA prevalence of 0.1%, consistent with literature. Though prevalence is low, due to unclear mechanisms and unreliable detection methods, BORSA may pose a therapeutic and epidemiological threat.
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来源期刊
Infection Prevention in Practice
Infection Prevention in Practice Medicine-Public Health, Environmental and Occupational Health
CiteScore
4.80
自引率
0.00%
发文量
58
审稿时长
61 days
期刊最新文献
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