迈向精准精神病学：抑郁症这块硬骨头

IF 52.7 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Signal Transduction and Targeted Therapy Pub Date : 2024-11-07 DOI:10.1038/s41392-024-02023-8

Juergen Dukart, Leon D. Lotter, Simon B. Eickhoff

{"title":"迈向精准精神病学：抑郁症这块硬骨头","authors":"Juergen Dukart, Leon D. Lotter, Simon B. Eickhoff","doi":"10.1038/s41392-024-02023-8","DOIUrl":null,"url":null,"abstract":"In a recent study published in Nature, Lynch et al.1 reported a consistent spatial expansion of the resting state salience network in subjects with major depression. The expansion was already present in children who later developed depression and remained stable over time in patients with depression, indicating a trait-like behavior of the observed endophenotype.","PeriodicalId":21766,"journal":{"name":"Signal Transduction and Targeted Therapy","volume":"33 1","pages":""},"PeriodicalIF":52.7000,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Moving towards precision psychiatry: the hard nut of depression\",\"authors\":\"Juergen Dukart, Leon D. Lotter, Simon B. Eickhoff\",\"doi\":\"10.1038/s41392-024-02023-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In a recent study published in Nature, Lynch et al.1 reported a consistent spatial expansion of the resting state salience network in subjects with major depression. The expansion was already present in children who later developed depression and remained stable over time in patients with depression, indicating a trait-like behavior of the observed endophenotype.\",\"PeriodicalId\":21766,\"journal\":{\"name\":\"Signal Transduction and Targeted Therapy\",\"volume\":\"33 1\",\"pages\":\"\"},\"PeriodicalIF\":52.7000,\"publicationDate\":\"2024-11-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Signal Transduction and Targeted Therapy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41392-024-02023-8\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Signal Transduction and Targeted Therapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41392-024-02023-8","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

Lynch 等人最近在《自然》（Nature）杂志上发表的一项研究1 报告称，重度抑郁症患者的静息状态显著性网络出现了持续的空间扩展。这种扩展在后来患上抑郁症的儿童身上已经出现，并且在抑郁症患者身上随着时间的推移保持稳定，这表明所观察到的内表型具有类似特质的行为。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

摘要图片

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Moving towards precision psychiatry: the hard nut of depression

In a recent study published in Nature, Lynch et al.¹ reported a consistent spatial expansion of the resting state salience network in subjects with major depression. The expansion was already present in children who later developed depression and remained stable over time in patients with depression, indicating a trait-like behavior of the observed endophenotype.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Signal Transduction and Targeted Therapy Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

44.50

自引率

1.50%

发文量

384

审稿时长

5 weeks

期刊介绍： Signal Transduction and Targeted Therapy is an open access journal that focuses on timely publication of cutting-edge discoveries and advancements in basic science and clinical research related to signal transduction and targeted therapy. Scope: The journal covers research on major human diseases, including, but not limited to: Cancer,Cardiovascular diseases,Autoimmune diseases,Nervous system diseases.