答复"重新评估虚弱与慢性肝病之间的因果关系：来自基因分析的证据"

IF 26.8 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Journal of Hepatology Pub Date : 2024-11-07 DOI:10.1016/j.jhep.2024.10.034

Qi Zhong, Hao-Wen Chen, Shun Zhang, Ji-Yuan Zhou, Xian-Bo Wu

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引用次数: 0

摘要

章节片段数据提供声明虚弱的GWAS汇总统计数据可从MRC-EU GWAS数据库（https://gwas.mrcieu.ac.uk/）下载。同样，肝脏疾病的 GWAS 统计摘要也可通过 FinnGen 财团获取 (https://r11.finngen.fi/)。作者贡献QZ、H-WC 和 SZ 起草了稿件并进行了主要的 MR 分析。X-BW 和 J-YZ 修改了手稿。本研究得到了国家自然科学基金[基金号：82173607、82173619]和广东省基础与应用基础研究基金[基金号：2021A1515011684、2024A1515011969]的资助。资助者在研究设计、数据收集或分析、数据解释、稿件撰写以及决定是否将论文提交发表等方面均未发挥作用。利益冲突声明本研究的作者声明他们没有任何利益冲突。致谢虚弱的GWAS汇总统计数据可从MRC-IEU GWAS数据库（https://gwas.mrcieu.ac.uk/）下载。同样，肝病的 GWAS 统计摘要也可通过 FinnGen 财团 (https://r11.finngen.fi/) 访问。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Reply to: “Reassessing the causal association between frailty and chronic liver disease: Evidence from genetic analyses”

Section snippets

Data availability statement

GWAS summary statistics for frailty are available for download from the MRC-IEU GWAS database (https://gwas.mrcieu.ac.uk/). Similarly, GWAS summary statistics for liver disease can be accessed through the FinnGen consortium (https://r11.finngen.fi/).

Authors’ contributions

QZ, H-WC, and SZ drafted the manuscript and performed the main MR analyses. X-BW and J-YZ revised the manuscript. All authors reviewed and approved the final manuscript.

Financial support

This study was supported by the National Natural Science Foundation of China [grant numbers 82173607, 82173619], and the Guangdong Basic and Applied Basic Research Foundation [grant numbers 2021A1515011684, 2024A1515011969]. The funders had no role in study design, data collection or analysis, data interpretation, manuscript writing, or decision to submit the paper for publication.

Declaration of Competing Interest

The authors of this study declare that they do not have any conflict of interest.

Acknowledgements

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来源期刊

Journal of Hepatology 医学-胃肠肝病学

CiteScore

46.10

自引率

4.30%

发文量

2325

审稿时长

30 days

期刊介绍： The Journal of Hepatology is the official publication of the European Association for the Study of the Liver (EASL). It is dedicated to presenting clinical and basic research in the field of hepatology through original papers, reviews, case reports, and letters to the Editor. The Journal is published in English and may consider supplements that pass an editorial review.