临床医生与视觉语言模型在放射学报告生成中的合作

IF 58.7 1区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Nature Medicine Pub Date : 2024-11-07 DOI:10.1038/s41591-024-03302-1
Ryutaro Tanno, David G. T. Barrett, Andrew Sellergren, Sumedh Ghaisas, Sumanth Dathathri, Abigail See, Johannes Welbl, Charles Lau, Tao Tu, Shekoofeh Azizi, Karan Singhal, Mike Schaekermann, Rhys May, Roy Lee, SiWai Man, Sara Mahdavi, Zahra Ahmed, Yossi Matias, Joelle Barral, S. M. Ali Eslami, Danielle Belgrave, Yun Liu, Sreenivasa Raju Kalidindi, Shravya Shetty, Vivek Natarajan, Pushmeet Kohli, Po-Sen Huang, Alan Karthikesalingam, Ira Ktena
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引用次数: 0

摘要

自动生成放射学报告具有改善患者护理和减轻放射科医生工作量的潜力。然而,评估人工智能(AI)生成的报告的临床质量一直是个难题,阻碍了实际应用之路。我们建立了一个最先进的胸部 X 光片报告生成系统,名为 Flamingo-CXR,并通过让一个由经委员会认证的放射科医生组成的小组参与进来,对人工智能生成的报告进行专家评估。我们观察到,专家小组成员和不同临床环境的偏好分布广泛,一半或一半以上的专家小组成员认为56.1%的Flamingo-CXR重症监护报告优于或等同于临床医生的报告,住院/门诊病人X光片的总体偏好比例上升到77.7%,无相关异常发现的病例子集偏好比例上升到94%。在人工报告和Flamingo-CXR报告中都发现了错误,其中24.8%的住院/门诊病例在两种报告类型中都存在临床重大错误,仅在Flamingo-CXR报告中存在22.8%的临床重大错误,仅在人工报告中存在14.0%的临床重大错误。对于含有错误的报告,我们开发了一种辅助设置,展示了临床医生与人工智能在放射学报告撰写方面的合作,为潜在的临床应用提供了新的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Collaboration between clinicians and vision–language models in radiology report generation

Automated radiology report generation has the potential to improve patient care and reduce the workload of radiologists. However, the path toward real-world adoption has been stymied by the challenge of evaluating the clinical quality of artificial intelligence (AI)-generated reports. We build a state-of-the-art report generation system for chest radiographs, called Flamingo-CXR, and perform an expert evaluation of AI-generated reports by engaging a panel of board-certified radiologists. We observe a wide distribution of preferences across the panel and across clinical settings, with 56.1% of Flamingo-CXR intensive care reports evaluated to be preferable or equivalent to clinician reports, by half or more of the panel, rising to 77.7% for in/outpatient X-rays overall and to 94% for the subset of cases with no pertinent abnormal findings. Errors were observed in human-written reports and Flamingo-CXR reports, with 24.8% of in/outpatient cases containing clinically significant errors in both report types, 22.8% in Flamingo-CXR reports only and 14.0% in human reports only. For reports that contain errors we develop an assistive setting, a demonstration of clinician–AI collaboration for radiology report composition, indicating new possibilities for potential clinical utility.

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来源期刊
Nature Medicine
Nature Medicine 医学-生化与分子生物学
CiteScore
100.90
自引率
0.70%
发文量
525
审稿时长
1 months
期刊介绍: Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.
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