苯胺与乙烯基氮丙啶在六氟异丙醇中的正烯丙基化反应

IF 4.6 1区化学 Q1 CHEMISTRY, ORGANIC Organic Chemistry Frontiers Pub Date : 2024-11-14 DOI:10.1039/d4qo01719f

Jing-Jing Nie, Zhong-Xia Wang

引用次数: 0

摘要

在六氟异丙醇中，N,N-二烷基苯胺与 1-磺酰基-2-乙烯基氮丙啶在空气中进行无过渡金属反应，可获得中等至极好收率的正烯丙基苯胺。该反应还具有反应条件温和、正单烯丙基化选择性高、C-C 双键为 E 构型、底物范围广以及官能团兼容性好等特点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Ortho-allylation of anilines with vinylaziridines in hexafluoroisopropanol

Transition-metal-free reaction of N,N-dialkylanilines with 1-sulfonyl-2-vinylaziridines in hexafluoroisopropanol in air gave ortho-allylated anilines in moderate to excellent yields. The reaction also features mild reaction conditions, ortho-monoallylation selectivity, E-configurated C-C double bonds, wide substrate scope and good compatibility of functional groups.

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来源期刊

Organic Chemistry Frontiers CHEMISTRY, ORGANIC-

CiteScore

7.90

自引率

11.10%

发文量

686

审稿时长

1 months

期刊介绍： Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.