{"title":"用于全髋关节置换术植入物定位有限元分析的非侵入式减阶模型。","authors":"Marlis Reiber, Fynn Bensel, Zhibao Zheng, Udo Nackenhorst","doi":"10.1007/s10237-024-01903-w","DOIUrl":null,"url":null,"abstract":"<p><p>Sophisticated high-fidelity simulations can predict bone mass density (BMD) changes around a hip implant after implantation. However, these models currently have high computational demands, rendering them impractical for clinical settings. Model order reduction techniques offer a remedy by enabling fast evaluations. In this work, a non-intrusive reduced-order model, combining proper orthogonal decomposition with radial basis function interpolation (POD-RBF), is established to predict BMD distributions for varying implant positions. A parameterised finite element mesh is morphed using Laplace's equation, which eliminates tedious remeshing and projection of the BMD results on a common mesh in the offline stage. In the online stage, the surrogate model can predict BMD distributions for new implant positions and the results are visualised on the parameterised reference mesh. The computational time for evaluating the final BMD distribution around a new implant position is reduced from minutes to milliseconds by the surrogate model compared to the high-fidelity model. The snapshot data, the surrogate model parameters and the accuracy of the surrogate model are analysed. The presented non-intrusive surrogate model paves the way for on-the-fly evaluations in clinical practice, offering a promising tool for planning and monitoring of total hip replacements.</p>","PeriodicalId":489,"journal":{"name":"Biomechanics and Modeling in Mechanobiology","volume":" ","pages":""},"PeriodicalIF":3.0000,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A non-intrusive reduced-order model for finite element analysis of implant positioning in total hip replacements.\",\"authors\":\"Marlis Reiber, Fynn Bensel, Zhibao Zheng, Udo Nackenhorst\",\"doi\":\"10.1007/s10237-024-01903-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Sophisticated high-fidelity simulations can predict bone mass density (BMD) changes around a hip implant after implantation. However, these models currently have high computational demands, rendering them impractical for clinical settings. Model order reduction techniques offer a remedy by enabling fast evaluations. In this work, a non-intrusive reduced-order model, combining proper orthogonal decomposition with radial basis function interpolation (POD-RBF), is established to predict BMD distributions for varying implant positions. A parameterised finite element mesh is morphed using Laplace's equation, which eliminates tedious remeshing and projection of the BMD results on a common mesh in the offline stage. In the online stage, the surrogate model can predict BMD distributions for new implant positions and the results are visualised on the parameterised reference mesh. The computational time for evaluating the final BMD distribution around a new implant position is reduced from minutes to milliseconds by the surrogate model compared to the high-fidelity model. The snapshot data, the surrogate model parameters and the accuracy of the surrogate model are analysed. The presented non-intrusive surrogate model paves the way for on-the-fly evaluations in clinical practice, offering a promising tool for planning and monitoring of total hip replacements.</p>\",\"PeriodicalId\":489,\"journal\":{\"name\":\"Biomechanics and Modeling in Mechanobiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-11-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomechanics and Modeling in Mechanobiology\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1007/s10237-024-01903-w\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOPHYSICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomechanics and Modeling in Mechanobiology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1007/s10237-024-01903-w","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOPHYSICS","Score":null,"Total":0}
A non-intrusive reduced-order model for finite element analysis of implant positioning in total hip replacements.
Sophisticated high-fidelity simulations can predict bone mass density (BMD) changes around a hip implant after implantation. However, these models currently have high computational demands, rendering them impractical for clinical settings. Model order reduction techniques offer a remedy by enabling fast evaluations. In this work, a non-intrusive reduced-order model, combining proper orthogonal decomposition with radial basis function interpolation (POD-RBF), is established to predict BMD distributions for varying implant positions. A parameterised finite element mesh is morphed using Laplace's equation, which eliminates tedious remeshing and projection of the BMD results on a common mesh in the offline stage. In the online stage, the surrogate model can predict BMD distributions for new implant positions and the results are visualised on the parameterised reference mesh. The computational time for evaluating the final BMD distribution around a new implant position is reduced from minutes to milliseconds by the surrogate model compared to the high-fidelity model. The snapshot data, the surrogate model parameters and the accuracy of the surrogate model are analysed. The presented non-intrusive surrogate model paves the way for on-the-fly evaluations in clinical practice, offering a promising tool for planning and monitoring of total hip replacements.
期刊介绍:
Mechanics regulates biological processes at the molecular, cellular, tissue, organ, and organism levels. A goal of this journal is to promote basic and applied research that integrates the expanding knowledge-bases in the allied fields of biomechanics and mechanobiology. Approaches may be experimental, theoretical, or computational; they may address phenomena at the nano, micro, or macrolevels. Of particular interest are investigations that
(1) quantify the mechanical environment in which cells and matrix function in health, disease, or injury,
(2) identify and quantify mechanosensitive responses and their mechanisms,
(3) detail inter-relations between mechanics and biological processes such as growth, remodeling, adaptation, and repair, and
(4) report discoveries that advance therapeutic and diagnostic procedures.
Especially encouraged are analytical and computational models based on solid mechanics, fluid mechanics, or thermomechanics, and their interactions; also encouraged are reports of new experimental methods that expand measurement capabilities and new mathematical methods that facilitate analysis.