一种基于纤维素胶的 CMC/PVA/SBA-15 生物相容性薄膜,可作为抗 MRSA 的胶体抗菌剂。

IF 3.9 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY RSC Advances Pub Date : 2024-11-13 DOI:10.1039/D4RA07129H
Shiva Pakzad, Reza Taghavi, Amir Hasanzadeh and Sadegh Rostamnia
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引用次数: 0

摘要

生物相容性抗菌薄膜的开发在对抗抗生素耐药菌株方面发挥着至关重要的作用。在此,我们开发了一种含有 Ag NPs 的 SBA-15-NH2 装饰生物相容性 CMC/PVA 薄膜,作为抗革兰氏阳性和革兰氏阴性菌株的抗菌材料。通过 XRD、SEM、制图和 TGA 分析研究了所制备薄膜的结构,结果表明其形成了牢固的结构。制备的薄膜具有柔性结构,因此适用于各种生物相关应用。CMC/PVA/SBA-15-NH2@AgNPs 薄膜被用作一种杀菌剂,用于对抗从手术部位感染中分离出来的病原体(尤其是 MRSA;耐甲氧西林金黄色葡萄球菌),结果令人满意。
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A biocompatible cellulose gum based CMC/PVA/SBA-15 film as a colloidal antibacterial agent against MRSA†

The development of biocompatible antibacterial films plays a crucial role in the fight against antibiotic-resistant bacteria strains. Here, we developed an SBA-15–NH2 decorated biocompatible CMC/PVA film containing Ag NPs as an antibacterial material against Gram-positive and Gram-negative bacteria strains. The structure of the manufactured film was studied by XRD, SEM, mapping, and TGA analysis showing its formation and firm structure. The prepared film has a flexible structure which makes it suitable for a variety of bio-related applications. The CMC/PVA/SBA-15–NH2@AgNPs film was used as a bactericidal agent against pathogens (especially MRSA; methicillin-resistant Staphylococcus aureus) isolated from surgical site infections, showing promising results.

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来源期刊
RSC Advances
RSC Advances chemical sciences-
CiteScore
7.50
自引率
2.60%
发文量
3116
审稿时长
1.6 months
期刊介绍: An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.
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