对服用精神药物的重症精神病患者进行常规代谢紊乱健康监测的评估:埃塞俄比亚的一项研究。

IF 3.4 2区 医学 Q2 PSYCHIATRY BMC Psychiatry Pub Date : 2024-11-12 DOI:10.1186/s12888-024-06266-1
Tirsit Ketsela Zeleke, Abel Hedato Teshome, Meron Tademe Assefa, Gashaw Sisay Chanie, Rahel Belete Abebe
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引用次数: 0

摘要

背景:与总体人群相比,有精神健康问题的患者更有可能同时患有躯体疾病,健康状况更差,死亡率更高。精神药物是治疗精神疾病的主要药物,但也会产生不良反应,如体重增加、血糖升高和循环血脂升高,所有这些都会导致代谢紊乱。健康监测不足可能会导致干预效果不佳和病情恶化。然而,目前还缺乏对埃塞俄比亚服用精神药物的重症精神病患者进行代谢紊乱及其决定因素的常规健康监测方法进行评估的研究。本研究旨在评估埃塞俄比亚服用精神药物的重症精神病患者代谢紊乱的常规健康监测及其决定因素:方法:对在 Debre Markos 综合专科医院精神科门诊就诊的服用精神药物的重症精神病患者进行了一项基于医院的前瞻性随访研究。采用简单随机抽样技术选出了符合条件的参与者。采用指南和以往文献对常规健康监测进行了评估。采用二元逻辑回归法确定常规健康监测的决定因素,统计意义由小于 0.05 的 p 值和 95% 的置信区间 (CI) 决定:结果表明:代谢性疾病的常规健康监测实践总体上并不理想。生命体征是最常评估的参数。常规健康监测的主要决定因素包括:参与者年龄在 45 岁及以上(AOR (95% CI):2.82 (1.34-5.92))、拥有社会保险(AOR (95% CI):2.94 (1.86-4.64))、医院提供实验室检测(AOR (95% CI):3.46 (2.16-5.55))以及报告药物相关副作用(AOR (95% CI):1.96 (1.21-3.17)):结论:对在精神科门诊就诊的重症精神病患者进行常规代谢紊乱健康监测是不够的。医疗服务提供者应更多地关注年轻患者、没有医疗保险的患者以及未报告副作用的患者。这些发现为改善常规健康监测和促进更好的健康结果提供了重要启示。
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Evaluation of routine health monitoring for metabolic disorders in patients with serious mental illness on psychotropic medications: a study from Ethiopia.

Background: Compared to the overall population, patients with mental health problems are more likely to experience concurrent physical illnesses, poorer health outcomes, and mortality. Psychotropic medications, which are the pillars in the management of mental health conditions, are associated with adverse effects such as weight gain, an increased level of glucose, and elevated circulating lipid levels, all of which contribute to metabolic disorders. Inadequate health monitoring may led to suboptimal interventions and worsening of these conditions. However, there is a lack of studies assessing routine health monitoring practices for metabolic disorders and their determinants among patients with serious mental illnesses taking psychotropic medications in Ethiopia. This study aimed to evaluate routine health monitoring for metabolic disorders and its determinants in patients with serious mental illnesses on psychotropic medications in Ethiopia.

Method: A hospital based prospective follow-up study was conducted among patients with serious mental illness taking psychotropic medications who attended the outpatient psychiatry department at Debre Markos Comprehensive Specialized Hospital. Eligible participants were selected using a simple random sampling technique. Routine health monitoring was evaluated using guidelines and previous literature. Binary logistic regression was employed to identify the determinants of routine health monitoring, with statistical significance determined by a p-value of less than 0.05 and a 95% confidence interval (CI).

Results: The overall routine health monitoring practice for metabolic disorders was found to be sub-optimal. Vital signs were the most commonly assessed parameters. Key determinants of routine health monitoring included participants aged 45 and above (AOR (95% CI): 2.82 (1.34-5.92), having social insurance (AOR (95% CI): 2.94 (1.86-4.64), availability of laboratory tests at the hospital (AOR (95% CI): 3.46 (2.16-5.55), and reporting of medication-related side effects (AOR (95% CI): 1.96 (1.21-3.17)).

Conclusion: Routine health monitoring for metabolic disorders in patients with serious mental illnesses attending the outpatient psychiatry department was inadequate. Health care providers should give more attention to younger patients, those without health insurance, and who are not reported side effects. These findings provide crucial insights for improving routine health monitoring and promoting better health outcomes.

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来源期刊
BMC Psychiatry
BMC Psychiatry 医学-精神病学
CiteScore
5.90
自引率
4.50%
发文量
716
审稿时长
3-6 weeks
期刊介绍: BMC Psychiatry is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of psychiatric disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
期刊最新文献
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