J López-Córdova, P Machuca, T Araya-Contreras, C Briceño-Montero, S Pérez-Tobar, P Faúndez Comte, M Castillo-Ruiz, M Bittner
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Positive samples were mainly from females (dogs: 52.8%; cats: 48.0%), with the highest infection rates in senior dogs (57.7%) and adult cats (45.4%). A single organism caused the infection in 78.2% of the cases, whereas the remaining 21.8% corresponded to a mixed infection. The most prevalent isolated pathogen in dogs and cats was Escherichia coli (42.6% and 49.7%, respectively). Staphylococcus spp. (15.6% and 14.6%), Enterococcus spp. (8.6% and 15.2%) and Proteus spp. (9.7% and 6.4%) were also commonly isolated. A total of 52.4% of Escherichia coli isolates were resistant to amoxicillin, 44.3% to amoxicillin/clavulanic acid, 40.0% to cephradine and 25.3% to ciprofloxacin. Regarding the other three uropathogens commonly isolated in this study, all of them showed a percentage of resistance to the antimicrobials analysed. In addition, 24.6% of multidrug resistance was detected in the E. coli isolates. Penicillin, cephalosporins and fluoroquinolones showed the lowest susceptibility levels.</p><p><strong>Clinical significance: </strong>The observed high rates of resistance to commonly prescribed antimicrobials raise concerns for public health.</p>","PeriodicalId":17062,"journal":{"name":"Journal of Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence and antimicrobial susceptibility profile of uropathogens in dogs and cats with signs of urinary tract infection.\",\"authors\":\"J López-Córdova, P Machuca, T Araya-Contreras, C Briceño-Montero, S Pérez-Tobar, P Faúndez Comte, M Castillo-Ruiz, M Bittner\",\"doi\":\"10.1111/jsap.13800\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>To determine the prevalence of uropathogens in dogs and cats with signs of urinary tract infection and to characterise their antimicrobial susceptibility.</p><p><strong>Materials and methods: </strong>Urine samples from canine and feline patients with clinical signs of urinary tract infection were collected between September 2015 and December 2019 in Santiago, Chile. Bacterial identification and bacterial susceptibility profile was performed through biochemical and antimicrobial susceptibility tests.</p><p><strong>Results: </strong>Four hundred sixty-six samples from dogs (37.7%) and 152 from cats (26.1%) showed bacterial growth. Positive samples were mainly from females (dogs: 52.8%; cats: 48.0%), with the highest infection rates in senior dogs (57.7%) and adult cats (45.4%). A single organism caused the infection in 78.2% of the cases, whereas the remaining 21.8% corresponded to a mixed infection. The most prevalent isolated pathogen in dogs and cats was Escherichia coli (42.6% and 49.7%, respectively). Staphylococcus spp. (15.6% and 14.6%), Enterococcus spp. (8.6% and 15.2%) and Proteus spp. (9.7% and 6.4%) were also commonly isolated. A total of 52.4% of Escherichia coli isolates were resistant to amoxicillin, 44.3% to amoxicillin/clavulanic acid, 40.0% to cephradine and 25.3% to ciprofloxacin. Regarding the other three uropathogens commonly isolated in this study, all of them showed a percentage of resistance to the antimicrobials analysed. In addition, 24.6% of multidrug resistance was detected in the E. coli isolates. 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Prevalence and antimicrobial susceptibility profile of uropathogens in dogs and cats with signs of urinary tract infection.
Objectives: To determine the prevalence of uropathogens in dogs and cats with signs of urinary tract infection and to characterise their antimicrobial susceptibility.
Materials and methods: Urine samples from canine and feline patients with clinical signs of urinary tract infection were collected between September 2015 and December 2019 in Santiago, Chile. Bacterial identification and bacterial susceptibility profile was performed through biochemical and antimicrobial susceptibility tests.
Results: Four hundred sixty-six samples from dogs (37.7%) and 152 from cats (26.1%) showed bacterial growth. Positive samples were mainly from females (dogs: 52.8%; cats: 48.0%), with the highest infection rates in senior dogs (57.7%) and adult cats (45.4%). A single organism caused the infection in 78.2% of the cases, whereas the remaining 21.8% corresponded to a mixed infection. The most prevalent isolated pathogen in dogs and cats was Escherichia coli (42.6% and 49.7%, respectively). Staphylococcus spp. (15.6% and 14.6%), Enterococcus spp. (8.6% and 15.2%) and Proteus spp. (9.7% and 6.4%) were also commonly isolated. A total of 52.4% of Escherichia coli isolates were resistant to amoxicillin, 44.3% to amoxicillin/clavulanic acid, 40.0% to cephradine and 25.3% to ciprofloxacin. Regarding the other three uropathogens commonly isolated in this study, all of them showed a percentage of resistance to the antimicrobials analysed. In addition, 24.6% of multidrug resistance was detected in the E. coli isolates. Penicillin, cephalosporins and fluoroquinolones showed the lowest susceptibility levels.
Clinical significance: The observed high rates of resistance to commonly prescribed antimicrobials raise concerns for public health.
期刊介绍：
Journal of Small Animal Practice (JSAP) is a monthly peer-reviewed publication integrating clinical research papers and case reports from international sources, covering all aspects of medicine and surgery relating to dogs, cats and other small animals. These papers facilitate the dissemination and implementation of new ideas and techniques relating to clinical veterinary practice, with the ultimate aim of promoting best practice. JSAP publishes high quality original articles, as well as other scientific and educational information. New developments are placed in perspective, encompassing new concepts and peer commentary. The target audience is veterinarians primarily engaged in the practise of small animal medicine and surgery.
In addition to original articles, JSAP will publish invited editorials (relating to a manuscript in the same issue or a topic of current interest), review articles, which provide in-depth discussion of important clinical issues, and other scientific and educational information from around the world.
The final decision on publication of a manuscript rests with the Editorial Board and ultimately with the Editor. All papers, regardless of type, represent the opinion of the authors and not necessarily that of the Editor, the Association or the Publisher.
The Journal of Small Animal Practice is published on behalf of the British Small Animal Veterinary Association and is also the official scientific journal of the World Small Animal Veterinary Association
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