L Carnegie, J T McCrone, L du Plessis, M Hasan, M Z Ali, R Begum, M Z Hassan, S Islam, M H Rahman, A S M Uddin, M S Sarker, T Das, M Hossain, M Khan, M H Razu, A Akram, S Arina, E Hoque, M M A Molla, T Nafisaa, P Angra, A Rambaut, S T Pullan, K L Osman, M A Hoque, P Biswas, M S Flora, J Raghwani, G Fournié, M A Samad, S C Hill
{"title":"孟加拉国早期 SARS-CoV-2 传播动态的基因组流行病学。","authors":"L Carnegie, J T McCrone, L du Plessis, M Hasan, M Z Ali, R Begum, M Z Hassan, S Islam, M H Rahman, A S M Uddin, M S Sarker, T Das, M Hossain, M Khan, M H Razu, A Akram, S Arina, E Hoque, M M A Molla, T Nafisaa, P Angra, A Rambaut, S T Pullan, K L Osman, M A Hoque, P Biswas, M S Flora, J Raghwani, G Fournié, M A Samad, S C Hill","doi":"10.1186/s12985-024-02560-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 spread in some of the world's least developed countries (LDCs).</p><p><strong>Methods: </strong>To begin to address this disparity, we studied the transmission dynamics of the virus in Bangladesh during the country's first COVID-19 wave by analysing case reports and whole-genome sequences from all eight divisions of the country.</p><p><strong>Results: </strong>We detected > 50 virus introductions to the country during the period, including during a period of national lockdown. Additionally, through discrete phylogeographic analyses, we identified that geographical distance and population -density and/or -size influenced virus spatial dispersal in Bangladesh.</p><p><strong>Conclusions: </strong>Overall, this study expands our knowledge of SARS-CoV-2 genomic epidemiology in Bangladesh, shedding light on crucial transmission characteristics within the country, while also acknowledging resemblances and differences to patterns observed in other nations.</p>","PeriodicalId":23616,"journal":{"name":"Virology Journal","volume":null,"pages":null},"PeriodicalIF":4.0000,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562509/pdf/","citationCount":"0","resultStr":"{\"title\":\"Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh.\",\"authors\":\"L Carnegie, J T McCrone, L du Plessis, M Hasan, M Z Ali, R Begum, M Z Hassan, S Islam, M H Rahman, A S M Uddin, M S Sarker, T Das, M Hossain, M Khan, M H Razu, A Akram, S Arina, E Hoque, M M A Molla, T Nafisaa, P Angra, A Rambaut, S T Pullan, K L Osman, M A Hoque, P Biswas, M S Flora, J Raghwani, G Fournié, M A Samad, S C Hill\",\"doi\":\"10.1186/s12985-024-02560-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 spread in some of the world's least developed countries (LDCs).</p><p><strong>Methods: </strong>To begin to address this disparity, we studied the transmission dynamics of the virus in Bangladesh during the country's first COVID-19 wave by analysing case reports and whole-genome sequences from all eight divisions of the country.</p><p><strong>Results: </strong>We detected > 50 virus introductions to the country during the period, including during a period of national lockdown. Additionally, through discrete phylogeographic analyses, we identified that geographical distance and population -density and/or -size influenced virus spatial dispersal in Bangladesh.</p><p><strong>Conclusions: </strong>Overall, this study expands our knowledge of SARS-CoV-2 genomic epidemiology in Bangladesh, shedding light on crucial transmission characteristics within the country, while also acknowledging resemblances and differences to patterns observed in other nations.</p>\",\"PeriodicalId\":23616,\"journal\":{\"name\":\"Virology Journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.0000,\"publicationDate\":\"2024-11-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562509/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Virology Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12985-024-02560-2\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"VIROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Virology Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12985-024-02560-2","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VIROLOGY","Score":null,"Total":0}
Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh.
Background: Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 spread in some of the world's least developed countries (LDCs).
Methods: To begin to address this disparity, we studied the transmission dynamics of the virus in Bangladesh during the country's first COVID-19 wave by analysing case reports and whole-genome sequences from all eight divisions of the country.
Results: We detected > 50 virus introductions to the country during the period, including during a period of national lockdown. Additionally, through discrete phylogeographic analyses, we identified that geographical distance and population -density and/or -size influenced virus spatial dispersal in Bangladesh.
Conclusions: Overall, this study expands our knowledge of SARS-CoV-2 genomic epidemiology in Bangladesh, shedding light on crucial transmission characteristics within the country, while also acknowledging resemblances and differences to patterns observed in other nations.
期刊介绍：
Virology Journal is an open access, peer reviewed journal that considers articles on all aspects of virology, including research on the viruses of animals, plants and microbes. The journal welcomes basic research as well as pre-clinical and clinical studies of novel diagnostic tools, vaccines and anti-viral therapies.
The Editorial policy of Virology Journal is to publish all research which is assessed by peer reviewers to be a coherent and sound addition to the scientific literature, and puts less emphasis on interest levels or perceived impact.
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