肝移植候选患者的超声心动图评估:从病理生理学到血液动力学优化。

Marta Iaconi, Micaela Maritti, Giuseppe Maria Ettorre, Luigi Tritapepe
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引用次数: 0

摘要

心血管并发症是严重肝病患者的常见病,也是围手术期和移植后发病率和死亡率的重要原因。肝硬化性心肌病(CCM)通常见于晚期肝病,其特征是舒张功能障碍、收缩功能障碍和电生理异常。虽然 CCM 在静息状态下可能不会引起症状,但在手术等紧张活动中会变得明显。肝移植虽然是终末期肝病(ESLD)的最终治疗方法,但也存在很大的心血管风险。术前心脏评估对于评估这些风险和计划适当的治疗至关重要。心脏成像,尤其是超声心动图,在评估肝移植候选者方面发挥着至关重要的作用,有助于识别诸如CCM、肺动脉高压、肝肺综合征等疾病。目前,肝移植麻醉师必须掌握超声心动图知识和技能,以评估移植患者的心血管状况,尤其是在术前阶段,以及术中和术后。
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Echocardiographic evaluation in patient candidate for liver transplant: from pathophysiology to hemodynamic optimization.

Cardiovascular complications are common in patients with severe liver disease and are an important cause of peri-operative and post-transplant morbidity and mortality. Cirrhotic cardiomyopathy (CCM), often found in advanced liver disease, is characterized by diastolic dysfunction, systolic dysfunction, and electrophysiological abnormalities. While CCM may not cause symptoms at rest, it can become evident during stressful activities, such as surgery. Liver transplantation, while being the definitive treatment for end-stage liver disease (ESLD), carries significant cardiovascular risks. Preoperative cardiac evaluation is essential for assessing these risks and planning appropriate management. Cardiac imaging, particularly echocardiography, plays a crucial role in evaluating liver transplant candidates, helping to identify conditions such as CCM, pulmonary hypertension, hepatopulmonary syndrome, and others. Currently, liver transplant anesthetists must acquire echocardiographic knowledge and skills to evaluate the cardiocirculatory conditions of the transplanted patient, especially in the pre-operative phase, but also intra-operatively and post-operatively.

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